Department of Pediatrics, Hasuda Issinkai Hospital, Saitama 349-0123, Japan.
Jpn J Infect Dis. 2013;66(1):22-5. doi: 10.7883/yoken.66.22.
The findings of this study revealed a 22% prevalence of Streptococcus pneumoniae among healthy children in Japan; the prevalence tended to increase with age. We identified attendance at day-care facilities and the presence of older siblings as the major risk factors associated with pneumococcal carriage. A significant decrease in pneumococcal colonization was observed among children during the summer; however, a seasonal variation was independent of various factors. Our findings suggest that prior immunization with heptavalent pneumococcal conjugate vaccine within the current recommended schedule is required for children exposed to these risk factors.
本研究发现，日本健康儿童中肺炎链球菌的患病率为 22%；该患病率随年龄增长而增加。我们发现，入托和有兄姐是与携带肺炎球菌相关的主要危险因素。在夏季，儿童的肺炎球菌定植显著减少；然而，季节性变化与各种因素无关。我们的研究结果表明，对于接触这些危险因素的儿童，需要按照当前推荐的免疫程序，提前接种 7 价肺炎球菌结合疫苗。
