13价肺炎球菌结合疫苗对法国东南部参加集体日托的儿童鼻咽部肺炎链球菌携带情况的影响。
Impact of the 13-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae among children attending group daycare in southeastern France.
作者信息
Dunais Brigitte, Bruno Pascale, Touboul Pia, Degand Nicolas, Sakarovitch Charlotte, Fontas Eric, Haas Hervé, Girard-Pipau Fernand, Ruimy Raymond, Pradier Christian
机构信息
From the *Public Health Department, and †Clinical Research Department, Nice University Hospital; ‡Fondation Lenval; and §Laboratoire de bactériologie, Nice University Hospital, Nice, France.
出版信息
Pediatr Infect Dis J. 2015 Mar;34(3):286-8. doi: 10.1097/INF.0000000000000559.
Regular surveys of pneumococcal nasopharyngeal carriage have been conducted among children attending daycare centers in Southeastern France from 1999 to 2012. We compared carriage rate, susceptibility patterns and serotype distribution in 2012, following implementation of the 13-valent pneumococcal conjugate vaccine, with findings from 5 previous surveys. Carriage rate was stable, antibiotic susceptibility improved and only serotype 19A persisted among vaccine-types.
1999年至2012年期间，对法国东南部日托中心的儿童进行了肺炎球菌鼻咽携带情况的定期调查。我们将2012年13价肺炎球菌结合疫苗实施后的携带率、药敏模式和血清型分布与之前5次调查的结果进行了比较。携带率稳定，抗生素敏感性提高，仅疫苗型中的19A血清型持续存在。
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