Pierrot-Deseilligny C
Service de neurologie et INSERM 289, hôpital de la Salpêtrière, Paris.
Rev Prat. 1990 May 1;40(13):1197-202.
Oculomotor palsies due to lesions of the brain stem may be complete, affecting all types of eye movements in one direction; this reflects a nuclear, internuclear or infractuclear lesion. This may also be disassociated, affecting only one type of eye movements, and this suggests supranuclear lesions. Concerting lateral movements, complete paralysis of abduction, adduction (sparing convergence) or ipsilateral laterality is suggestive of damage to the radicular fibres of the abducencs nucleus (VI), to its internuclear neurons or to the nucleus itself respectively. Isolated paralysis of saccades is in favour of a lesion of the paramedian pontine reticular formation. As regards vertical movements, paralysis of the oculomotor nerve (III), either isolated or associated with complete paralysis of the contralateral rectus superior oculi muscle, suggests a lesion of the radicular fibres of III or of the nucleus itself respectively. Paralysis of downward or both downward and upward saccades indicates the presence of bilateral lesions in the region of the mesencephalic reticular formation. Paralysis of upward saccades alone reflects a unilateral lesion located near the posterior commissure.
脑干病变导致的动眼神经麻痹可能是完全性的,影响一个方向上的所有眼球运动类型;这反映了核性、核间性或核下性病变。也可能是分离性的,仅影响一种眼球运动类型,这提示核上性病变。关于水平运动,外展、内收(保留集合)或同侧偏斜的完全性麻痹分别提示展神经核(Ⅵ)的根纤维、其核间神经元或核本身受损。单独的扫视麻痹提示脑桥旁正中网状结构病变。关于垂直运动,动眼神经(Ⅲ)麻痹,无论是单独出现还是与对侧上直肌完全麻痹相关,分别提示Ⅲ的根纤维或核本身病变。向下或向下及向上扫视麻痹表明中脑网状结构区域存在双侧病变。仅向上扫视麻痹反映位于后连合附近的单侧病变。