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[植物芳香物质对大鼠血液和肝脏中各种酶活性的影响]

[The effect of plant aromatic substances on the activity of various enzymes in the rat blood and liver].

作者信息

Nikolaevskiĭ V V, Iurkova O F, Ivanov I K, Gerzhikova V G

出版信息

Vopr Med Khim. 1990 Jan-Feb;36(1):31-3.

PMID:2343571
Abstract

Enzymatic activity was studied in blood plasma, erythrocytes and liver tissue homogenate of rats treated with vegetable aromatic substances. 60 rats were kept within 3 months in atmosphere containing naturally occurring concentrations of monarde ester oil. Control animals were maintained in usual atmosphere of vivarium. In liver tissues of control animals glycolytic processes predominated as shown by the data on increased activities of lactate- and glucose-6-phosphate dehydrogenases. At the same time, activity of soluble microsomal enzyme acetyl esterase was decreased in liver tissue, while activity of these esterases was increased in blood plasma, thus suggesting that membrane structures were destabilized. Aromatic fractions of monarde ester oil, introduced into atmosphere, contributed to normalization of the enzymatic reactions studied.

摘要

对用植物芳香物质处理的大鼠的血浆、红细胞和肝组织匀浆中的酶活性进行了研究。60只大鼠在含有天然浓度的薄荷酯油的大气中饲养3个月。对照动物饲养在饲养室的正常大气环境中。对照动物肝脏组织中的糖酵解过程占主导,这由乳酸脱氢酶和葡萄糖-6-磷酸脱氢酶活性增加的数据表明。同时,肝组织中可溶性微粒体酶乙酰酯酶的活性降低,而这些酯酶在血浆中的活性增加,这表明膜结构不稳定。引入大气中的薄荷酯油的芳香成分有助于所研究的酶促反应正常化。

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