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[从古巴国家动物园的一只猎豹(猎豹属)中分离出的加氏隐球菌]

[Cyptococcus gattii isolated from a cheetah (Acinonyx jubatus) in the National Zoo of Cuba].

作者信息

Polo Leal Jorge Luis, Fernández Andreu Carlos Manuel, Martínez Machín Gerardo, Illnait Zaragozi María Teresa, Perurena Lancha Mayda Rosa

机构信息

Parque Zoológico Nacional, Ciudad de La Habana, Cuba.

出版信息

Rev Cubana Med Trop. 2010 Sep-Dec;62(3):257-60.

Abstract

INTRODUCTION

Cryptoccosis--systemic mycosis caused by Cryptococcus species--has considerably raised its incidence in the last years, mainly associated with the human immunodeficiency virus infection. It has also been described in animals, but rare cases.

METHODS

a case of a female cheetah (Acinonyx jubatus) kept in the Nacional Zoo of Havana was presented. The animal came from South Africa. She began losing weight, and suffering asthenia, anorexia and breathing problems with abundant nasal secretion.

RESULTS

mycological testing of these secretions disclosed the presence of serotype B Cryptococcus gattii. Because of the origin and captive condition of the animal, it was believed that the infection had been latent for 16 months at least.

CONCLUSIONS

up to the present, in Cuba, all clinical Cryptococcus isolates were C. neoformans var. grubii, so it is considered that the infection was caught in the country of origin of the female cheetah. This is the first C. gattii isolate in Cuba from an animal coming from South Africa where this fungus is endemic.

摘要

引言

隐球菌病——由隐球菌属引起的系统性真菌病——在过去几年中发病率大幅上升,主要与人类免疫缺陷病毒感染有关。在动物中也有相关报道,但病例罕见。

方法

介绍了一例饲养在哈瓦那国家动物园的雌性猎豹(猎豹属)病例。这只动物来自南非。它开始体重减轻,并出现乏力、厌食和呼吸问题,伴有大量鼻腔分泌物。

结果

对这些分泌物进行真菌学检测发现了血清型B的加氏隐球菌。鉴于该动物的来源和圈养情况,据信感染至少已潜伏16个月。

结论

到目前为止,在古巴,所有临床分离的隐球菌均为新型隐球菌格鲁比变种,因此认为该感染是在雌性猎豹的原产国感染的。这是古巴首次从来自南非(该真菌为地方病流行区)的动物身上分离出加氏隐球菌。

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