Walser-Reinhardt Ladina, Wernick Morena B, Hatt Jean-Michel, Spiess Bernhard M
Equine Department, Section of Ophthalmology, Vetsuisse Faculty, University of Zurich, Switzerland.
Vet Ophthalmol. 2010 Sep;13 Suppl:128-33. doi: 10.1111/j.1463-5224.2010.00809.x.
The following case report describes a 1-year-old female cheetah (Acinonyx jubatus) with bilateral blindness and unresponsive pupils. For comparison, a second healthy 2.5-year-old male cheetah without visual deficits was also examined. Clinical examination of both animals included biomicroscopy, indirect ophthalmoscopy, tonometry, and electroretinography. The young female cheetah showed no menace response, no direct or indirect pupillary light reflex, and no dazzle reflex in either eye. Fundus lesions, as detected by indirect ophthalmoscopy, are described for the female animal. In both eyes, the fundus color was green/turquoise/yellow with multiple hyperpigmented linear lesions in the tapetal area around the optic nerve. The optic nerve head was dark gray and about half the normal size suggesting bilateral optic nerve hypoplasia and retinal dysplasia or differentially optic nerve atrophy and chorioretinal scarring. The ERG had low amplitudes in the right eye but appeared normal in the left eye compared with the male cheetah. Blood levels did not suggest current taurine deficiency. This is addressed to some degree in the discussion. Bilateral optic nerve hypoplasia or optic nerve atrophy is a rare anomaly in cats and has not yet been described in a cheetah.
以下病例报告描述了一只1岁雌性猎豹（猎豹属），双眼失明且瞳孔无反应。作为对照，还对一只没有视觉缺陷的2.5岁健康雄性猎豹进行了检查。对两只动物的临床检查包括生物显微镜检查、间接检眼镜检查、眼压测量和视网膜电图检查。这只年轻的雌性猎豹两只眼睛均无威胁反应、直接或间接瞳孔对光反射以及闪光反射。通过间接检眼镜检查发现的雌性动物眼底病变情况如下。两只眼睛的眼底颜色为绿色/蓝绿色/黄色，在视神经周围的反光区域有多个色素沉着的线性病变。视神经乳头呈深灰色，约为正常大小的一半，提示双侧视神经发育不全和视网膜发育异常，或不同程度的视神经萎缩和脉络膜视网膜瘢痕形成。与雄性猎豹相比，该雌性猎豹右眼的视网膜电图振幅较低，而左眼看起来正常。血液检测结果未提示当前存在牛磺酸缺乏。这在讨论中会在一定程度上有所涉及。双侧视神经发育不全或视神经萎缩在猫中是一种罕见的异常情况，尚未在猎豹中被描述过。
