金对小鼠免疫反应的影响。
Effect of gold on the immune response of mice.
作者信息
Measel J W
出版信息
Infect Immun. 1975 Feb;11(2):350-4. doi: 10.1128/iai.11.2.350-354.1975.
Abstract
Separate concurrent injection of organic gold compounds and antigen into mice resulted in immunoenhancement that could be measured by direct and indirect plaque-forming cells, rosette-forming cells, and serum antibody assays. Kinetics of the immune response showed variable effects through day 9 of the experiment. Studies with British anti-lewisite, a gold antagonist, showed that the gold must stay in the system 1 day to obtain immunoenhancement.
摘要
将有机金化合物和抗原同时分别注射到小鼠体内，可产生免疫增强作用，这可通过直接和间接空斑形成细胞、玫瑰花结形成细胞以及血清抗体检测来衡量。免疫反应的动力学在实验第9天前呈现出不同的效应。使用金拮抗剂二巯基丙醇进行的研究表明，金必须在体内留存1天才能实现免疫增强。
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