Bergfeld J, Rubo B, Krey M, George G
Forschungszentrum für Tierproduktion Dummerstorf, Rostock der Akademie der Landwirtschaftswissenschaften der DDR.
Arch Exp Veterinarmed. 1990;44(1):11-8.
Treatment was applied, on two farms, to 272 gilts and 169 adult sows, 24 hours after discontinuation of Suisynchron application to the gilts or weaning of piglets of adult sows. Included were 600, 800 or 1,000 IU of PMSG for the gilts and 750, 1,000 oder 1,250 IU of the same batch (Pregmagon-Dessau) for the adult sows for ovarian stimulation. This was followed by application of 500 IU of HCG to the gilts or 300 micrograms Gn-RH vet. "Berlin-Chemie" + 300 IU HCG to the adult sows for synchronised ovulation. Laparotomy was performed on the gilts on the fifth day from PMSG application and on the adult sows on the fourth day. Average ovariotropic stimulation was "mild" in response to lower doses (14.8 follicles in gilts and 20.4 follicles in adult sows) but was "pronounced" in response to medium doses (19.4 or 22.7 follicles, respectively). The pharmacological concept of "mild" exogenic ovarian stimulation by low dosage at the threshold of effectiveness should deserve more attention, last but not least, for breeding aspects. The two groups of animals on both farms differed considerably from one another with regard to reactivity, which cannot be etiologically interpreted for the time being.
在两个农场,对272头后备母猪和169头成年母猪进行了治疗,时间是在后备母猪停止使用苏伊同步素或成年母猪仔猪断奶24小时后。对后备母猪使用600、800或1000国际单位的孕马血清促性腺激素(PMSG),对成年母猪使用同一批次(Pregmagon - Dessau)的750、1000或1250国际单位进行卵巢刺激。随后,对后备母猪注射500国际单位的人绒毛膜促性腺激素(HCG),对成年母猪注射300微克的兽用促性腺激素释放激素(Gn - RH)“柏林化学公司” + 300国际单位的HCG以同步排卵。在注射PMSG后的第五天对后备母猪进行剖腹手术,对成年母猪在第四天进行剖腹手术。低剂量时平均促卵泡刺激为“轻度”(后备母猪有14.8个卵泡,成年母猪有20.4个卵泡),但中等剂量时为“显著”(分别为19.4个或22.7个卵泡)。低剂量在有效阈值下进行“轻度”外源性卵巢刺激的药理学概念,至少在育种方面应得到更多关注。两个农场的两组动物在反应性方面差异很大,目前无法从病因学上进行解释。