Brüssow K P, Bergfeld J
Arch Exp Veterinarmed. 1981;35(2):285-90.
Combinations of pregnant mare serum gonadotrophin (PMSG) with Gn-RH were tested for ovulation-triggering action on 93 prepuberal gilts, aged between 185 and 210 days. The action of PMSG was somewhat inhibited by Gn-RH, when 500 IU of PMSG were given together with 600 micrograms or 900 micrograms of Gn-RH. An infection of 900 micrograms Gn-RH, applied three days from PMSG administration, caused ovulations in 83 per cent of the animals up to the fifth day from PMSG administration on which laparotomy was performed. Smaller intervals of one or two days caused the same effect on 25 or eight per cent of the animals. The presence of a sufficiently high number of graafian follicles suggested pronounced overreaction to all variants of treatment, using PMSG alone or in combination with Gn-RH. The effect of lower Gn-RH doses seems worthwhile another study.
对93头年龄在185至210天之间的青春期前小母猪，测试了孕马血清促性腺激素（PMSG）与促性腺激素释放激素（Gn-RH）联合使用对排卵的触发作用。当500国际单位的PMSG与600微克或900微克的Gn-RH一起给药时，Gn-RH对PMSG的作用有一定程度的抑制。在给予PMSG三天后注射900微克Gn-RH，在进行剖腹手术的PMSG给药后第五天，83%的动物排卵。间隔一或两天较短时间给药，分别使25%或8%的动物产生相同效果。存在足够数量的格拉夫卵泡表明，单独使用PMSG或与Gn-RH联合使用时，对所有治疗方案均有明显的过度反应。较低剂量Gn-RH的效果似乎值得进一步研究。
