Department of Psychiatry, The University of Western Ontario, London, Ontario, Canada.
Can J Psychiatry. 2013 Feb;58(2):99-106. doi: 10.1177/070674371305800207.
People with borderline personality disorder (BPD) are at high risk for attempting suicide. There are some data to suggest that risk factors for suicide attempts change over time. We conducted a prospective cohort study to examine risk factors for suicide attempts in a treated sample of patients with BPD.
One hundred eighty participants with BPD were followed over a year-long course of dialectical behaviour therapy or general psychiatric management and then for 2 more years in naturalistic follow-up. Participants were assessed for suicidal and self-injurious behaviours at baseline, every 4 months over the 1-year treatment phase, and every 6 months over a 2-year follow-up period. Participants were classified as suicide or non-suicide attempters based on their behaviour at the end of the 1-year treatment phase and after the 2-year follow-up period. Groups were then compared on baseline clinical and demographic variables.
Nearly 26% of participants made a suicide attempt during the 1-year treatment phase, while 16.7% reported a suicide attempt over the 2-year follow-up period. Baseline number of suicide attempts during the 4 months prior to study and severity of childhood sexual abuse predicted suicide attempts during the treatment year. Similarly, baseline suicide attempts, severity of childhood sexual abuse, and number of hospitalizations in the 4 months prior to study entry predicted suicide attempts during the 2-year follow-up.
Risk factors for suicide attempts in this treated sample of patients with BPD were fairly stable, largely non-modifiable, and unrelated to psychopathology or psychosocial functioning at baseline.
边缘型人格障碍(BPD)患者自杀风险很高。有一些数据表明,自杀尝试的风险因素会随时间而变化。我们进行了一项前瞻性队列研究,以检查 BPD 患者治疗样本中自杀尝试的风险因素。
180 名 BPD 参与者接受了为期一年的辩证行为治疗或一般精神科管理,然后在自然随访中再进行两年的随访。参与者在基线、治疗期的每 4 个月以及随访期的每 6 个月接受自杀和自残行为评估。根据治疗期结束时和 2 年随访期结束时的行为,将参与者分为自杀或非自杀尝试者。然后比较两组在基线时的临床和人口统计学变量。
近 26%的参与者在治疗期的一年内尝试自杀,而 16.7%的参与者在 2 年随访期内报告自杀。在研究开始前的 4 个月内自杀尝试的次数和儿童期性虐待的严重程度预测了治疗年内的自杀尝试。同样,基线自杀尝试、儿童期性虐待的严重程度以及在研究开始前的 4 个月内的住院次数预测了 2 年随访期间的自杀尝试。
在这个接受治疗的 BPD 患者样本中,自杀尝试的风险因素相当稳定,主要是不可改变的,与基线时的精神病理学或社会心理功能无关。