Van Haltren Karen, Malhotra Atul
Department of Paediatrics, Monash University, Melbourne, Victoria, Australia.
J Pediatr Endocrinol Metab. 2013;26(5-6):525-9. doi: 10.1515/jpem-2013-0009.
Neonatal hypoglycemia is a common symptom in early infant life. The currently available literature identifies the risk factors but not the degree to which each factor lends itself to the development or severity of an ensuing hypoglycemia.
A retrospective electronic chart review of near-term and term infants (>35 weeks' gestation) admitted to a tertiary-level neonatal unit over 16 months was carried out from the initiation of electronic record keeping.
Ninety-five infants admitted with hypoglycemia to the unit were identified with complete records available. Fifty-eight percent of the infants were males, and the median gestation was 38 weeks. Twenty-two percent of the infants were premature, whereas 18% were macrosomic. Maternal diabetes was present in 27% infants. Comorbidities were common in this cohort, with approximately two-thirds of infants having multiple morbidities. The majority of which were jaundice and infection, whereas the minor ones were respiratory distress, initial lactic acidosis, feeding issues, and temperature instability.
Neonatal hypoglycemia continues to be a significant morbidity in near-term and term infants. The presence of multiple morbidities is common in the setting of hypoglycemia and is the main determinant of the length of stay in the neonatal unit in this study population.
新生儿低血糖是婴儿早期的常见症状。现有文献确定了风险因素,但未明确各因素对随后发生低血糖的发展或严重程度的影响程度。
从电子记录开始保存起,对一家三级新生儿病房16个月内收治的近足月儿和足月儿(孕周>35周)进行回顾性电子病历审查。
确定95例因低血糖入院的婴儿有完整可用记录。58%的婴儿为男性,中位孕周为38周。22%的婴儿早产,18%为巨大儿。27%的婴儿母亲患有糖尿病。该队列中合并症很常见,约三分之二的婴儿有多种合并症。其中大多数是黄疸和感染,少数是呼吸窘迫、初始乳酸酸中毒、喂养问题和体温不稳定。
新生儿低血糖仍是近足月儿和足月儿的重要发病情况。在低血糖情况下,多种合并症很常见,并且是本研究人群在新生儿病房住院时间的主要决定因素。