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New set of Alzheimer's trials focus on prevention.

作者信息

Corbyn Zoë

出版信息

Lancet. 2013 Feb 23;381(9867):614-5. doi: 10.1016/s0140-6736(13)60330-x.

DOI:10.1016/s0140-6736(13)60330-x
PMID:23444487
Abstract
摘要

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New set of Alzheimer's trials focus on prevention.新一轮阿尔茨海默病试验聚焦于预防。
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New and different approaches needed for the design and execution of Alzheimer's clinical trials.阿尔茨海默病临床试验的设计与实施需要新的不同方法。
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Amyloid-related imaging abnormalities-haemosiderin (ARIA-H) in patients with Alzheimer's disease treated with bapineuzumab: a historical, prospective secondary analysis.接受巴宾纽单抗治疗的阿尔茨海默病患者的淀粉样蛋白相关成像异常-含铁血黄素（ARIA-H）：一项历史性前瞻性二次分析
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Can we do better in developing new drugs for Alzheimer's disease?我们能否在开发阿尔茨海默病新药方面做得更好？
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Clinical Effects of Tramiprosate in APOE4/4 Homozygous Patients with Mild Alzheimer's Disease Suggest Disease Modification Potential.载脂蛋白 E4/4 纯合子轻度阿尔茨海默病患者中曲美吉林的临床疗效提示具有疾病修饰潜力。
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Tramiprosate.曲美司他。
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Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD Task Force.设计阿尔茨海默病药物临床试验：从 III 期抗体试验结果发布中得到的经验教训：来自欧盟/美国/CTAD 工作组的报告。
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