Department of Immunopathology, Post Graduate Institute of Medical Education & Research, Chandigarh 160012, India.
Expert Rev Clin Immunol. 2013 Mar;9(3):211-26. doi: 10.1586/eci.12.104.
Allergic disorders are a group of immune-mediated disorders that are associated with considerable morbidity and ill health. There has been significant rise in the prevalence of allergy in the last few years. This has heightened interest in uncovering the novel mechanisms involved in etiopathogenesis of allergic disorders. Understanding the pathways underlying allergy will help in developing effective modalities for its prevention and treatment. This review focuses primarily on common IgE-mediated allergic conditions and recent developments in their immunopathogenesis, especially those involving respiratory mucosa.
过敏症是一组与相当大的发病率和健康不良有关的免疫介导疾病。在过去几年中，过敏的患病率显著上升。这提高了人们对揭示过敏症发病机制中涉及的新机制的兴趣。了解过敏症的潜在途径将有助于开发有效的预防和治疗方法。本综述主要集中在常见的 IgE 介导的过敏疾病及其免疫发病机制的最新进展，特别是涉及呼吸道黏膜的那些。
