Treska V, Valenta J, Emmerová M
Chirurgická klinika fakultní nemocnice, Plzen.
Cas Lek Cesk. 1990 Apr 6;129(14):429-31.
The authors submit their initial experience with fibrinolytic treatment of acute arterial occlusions. In a group of 14 patients streptokinase and urokinase was administered 12 times as general treatment and twice locally. Treatment was successful in seven patients, no change in the local finding was recorded in two patients, in another two patients despite treatment progression of the ischaemia occurred. Two patients died in causal relation with treatment, one patient died for other reasons. Based on their own experience and that of authors abroad the authors emphasize the necessity of strict indication for fibrinolytic treatment, they prefer local to general administration, with regard to the number of complications. In the authors' opinion fibrinolysis holds a justified position in the treatment of acute arterial occlusions as a supplementary method of surgical treatment.
作者介绍了他们使用纤维蛋白溶解疗法治疗急性动脉闭塞的初步经验。在一组14例患者中，链激酶和尿激酶作为全身治疗给药12次，局部给药2次。7例患者治疗成功，2例患者局部情况无变化记录，另外2例患者尽管接受了治疗，但缺血仍有进展。2例患者因治疗相关原因死亡，1例患者因其他原因死亡。基于他们自己的经验以及国外作者的经验，作者强调了纤维蛋白溶解疗法严格适应症的必要性，考虑到并发症的数量，他们更倾向于局部给药而非全身给药。作者认为，作为手术治疗的辅助方法，纤维蛋白溶解疗法在急性动脉闭塞的治疗中占有合理的地位。
