Heidemann S M, Sarnaik A P
Department of Pediatrics, Henry Ford Hospital, Detroit, MI.
Crit Care Med. 1990 Jun;18(6):618-20. doi: 10.1097/00003246-199006000-00008.
Fourteen cases of severe clonidine poisoning occurring in children over a 5-yr period were reviewed. The typical patient was a previously healthy toddler who ingested clonidine while visiting a relative. All patients were lethargic on admission and most were admitted with bradycardia or miosis. Hypotension was more likely to develop after admission. Recovery occurred within 48 h with only symptomatic treatment. Significant morbidity from clonidine ingestion occurred in terms of hospitalization, invasive monitoring, and mechanical ventilation.
回顾了5年期间发生的14例儿童严重可乐定中毒病例。典型患者是之前健康的幼儿，在探亲时摄入了可乐定。所有患者入院时均嗜睡，大多数患者因心动过缓或瞳孔缩小入院。入院后更易出现低血压。仅进行对症治疗，患者在48小时内康复。可乐定摄入导致了住院、侵入性监测和机械通气方面的显著发病率。
