Department of Medical Psychology and Neuropsychology, Center of Research on Psychology in Somatic Diseases, Tilburg University, Warandelaan 2, PO Box 90153, 5000 LE Tilburg, The Netherlands.
Endocr Relat Cancer. 2013 Mar 26;20(2):263-71. doi: 10.1530/ERC-12-0336. Print 2013 Apr.
The incidence of thyroid cancer (TC) is increasing worldwide, partly due to increased detection. We therefore assessed combined trends in incidence, survival and mortality of the various types of TC in The Netherlands between 1989 and 2009. We included all patients ≥15 years with TC, diagnosed in the period 1989-2009 and recorded in The Netherlands Cancer Registry (n=8021). Information on age, gender, date of diagnosis, histological type of tumour and tumour-node-metastasis classification was recorded. Mortality data (up to 1st January 2010) were derived from Statistics Netherlands. Annual percentages of change in incidence, mortality and relative survival were calculated. Since 1989 the incidence of TC increased significantly in The Netherlands (estimated annual percentage change (EAPC)=+1.7%). The incidence rates increased for all age groups (except for females >60 years), papillary tumours (EAPC=+3.5%), T1 and T3 TC (EAPC=+7.9 and +5.8% respectively). Incidence rates decreased for T4 TC (-2.3%) and remained stable for follicular, medullary anaplastic and T2 TC. Five-year relative survival rates remained stable for papillary (88%) and follicular (77%) TC, all age groups and T1-T3 TC (96, 94 and 80% respectively) and somewhat lower for T4 (53%), medullary (65%) and anaplastic TC (5%) in the 2004-2009 period compared with earlier periods. Mortality due to TC decreased (EAPC=-1.9%). TC detection and incidence has been rising in The Netherlands, while mortality rates are decreasing and survival rates remained stable or slightly decreasing.
甲状腺癌（TC）的发病率在全球范围内呈上升趋势，部分原因是检测的增加。因此，我们评估了 1989 年至 2009 年荷兰各种类型 TC 的发病率、生存率和死亡率的综合趋势。我们纳入了所有在 1989 年至 2009 年期间诊断为 TC 的年龄≥15 岁的患者，并记录在荷兰癌症登记处（n=8021）。记录了年龄、性别、诊断日期、肿瘤的组织学类型和肿瘤-淋巴结-转移分类。死亡率数据（截至 2010 年 1 月 1 日）来自荷兰统计局。计算了发病率、死亡率和相对生存率的年变化百分比。自 1989 年以来，荷兰 TC 的发病率显著增加（估计年变化百分比（EAPC）=+1.7%）。所有年龄组（60 岁以上女性除外）、乳头状肿瘤（EAPC=+3.5%）、T1 和 T3 TC（EAPC=+7.9%和+5.8%）的发病率均增加。T4 TC 的发病率（-2.3%）下降，滤泡性、髓样间变性和 T2 TC 的发病率保持稳定。5 年相对生存率在乳头状（88%）和滤泡性（77%）TC 以及所有年龄组和 T1-T3 TC（分别为 96%、94%和 80%）中保持稳定，而在 T4（53%）、髓样（65%）和间变性 TC（5%）中则略有下降2004-2009 年与早期相比。TC 死亡率下降（EAPC=-1.9%）。荷兰 TC 的检出率和发病率上升，而死亡率下降，生存率保持稳定或略有下降。
