神经内分泌学与边缘叶癫痫：与精神病理学、癫痫发作变量及神经心理功能的关系。

Neuroendocrinology and limbic epilepsy: relationships to psychopathology, seizure variables, and neuropsychological function.

作者信息

Leiderman D B, Csernansky J G, Moses J A

机构信息

Department of Neurology, Stanford University School of Medicine, California.

出版信息

Epilepsia. 1990 May-Jun;31(3):270-4. doi: 10.1111/j.1528-1157.1990.tb05375.x.

DOI:10.1111/j.1528-1157.1990.tb05375.x

PMID:2344844

Abstract

Correlations were sought among neuroendocrine, psychopathologic, neuropsychological, and seizure variables in 16 male patients with limbic epilepsy. Plasma prolactin and luteinizing hormone levels were directly correlated with seizure frequency. Plasma prolactin was inversely correlated with thought disorder. Post hoc findings included a strong direct correlation between total plasma testosterone levels and aggression. These relationships may help to elucidate mechanisms related to interictal symptomatology in patients with limbic epilepsy.

摘要

在16例边缘性癫痫男性患者中，对神经内分泌、精神病理学、神经心理学和癫痫发作变量之间的相关性进行了研究。血浆催乳素和促黄体生成素水平与癫痫发作频率直接相关。血浆催乳素与思维障碍呈负相关。事后分析结果显示，血浆总睾酮水平与攻击性之间存在强烈的直接相关性。这些关系可能有助于阐明边缘性癫痫患者发作间期症状学的相关机制。