Wang Xiao-Qing, Wang Chuan-Chao, Deng Qiong-Ying, Li Hui
Department of Anatomy, Guangxi Medical University, Nanning, China.
Yi Chuan. 2013 Feb;35(2):168-74. doi: 10.3724/sp.j.1005.2013.00168.
In order to study the molecular genetic structure of Mulam ethnic group in Guangxi, China, Y chromosome and mitochondrial DNA(mtDNA)polymorphisms were genotyped. High frequencies of the Y chromosome haplogroups O1a1-P203 and O2a1*-M95 were found in Mulam, exhibiting a pattern similar to the neighboring indigenous populations, especially the Daic populations. MtDNA lineages F1a, M*, B4a, B5a, M7b, and N9a were found in Mulam, which always present at high frequencies among the populations of East Asia. Mulam exhibits genetic characteristics of southern Chinese in both paternal and maternal lineages. Multiplex detection of the 17 Y-STR loci and mtDNA HVS-I revealed the distribu-tion of highly genetic diversity in Mulam, which would have potential application in population genetics and forensic practice.
为研究中国广西仫佬族的分子遗传结构，对Y染色体和线粒体DNA（mtDNA）多态性进行了基因分型。在仫佬族中发现Y染色体单倍群O1a1-P203和O2a1*-M95的频率较高，呈现出与邻近土著群体，特别是侗傣语族群体相似的模式。在仫佬族中发现了线粒体谱系F1a、M*、B4a、B5a、M7b和N9a，这些谱系在东亚人群中总是以高频率出现。仫佬族在父系和母系谱系中均表现出中国南方人的遗传特征。对17个Y-STR基因座和mtDNA高变区I的多重检测揭示了仫佬族高度遗传多样性的分布情况，这在群体遗传学和法医学实践中具有潜在应用价值。
