Department of Neurology, Chi Mei Medical Center, Tainan, Taiwan.
Stroke. 2013 Apr;44(4):1182-5. doi: 10.1161/STROKEAHA.111.000663. Epub 2013 Feb 28.
It is not known how many stroke patients die from fatal pulmonary complications such as aspiration pneumonia (AP) and choking each year in the United States. This study aimed to determine the frequency of reporting of AP or choking as a cause of death on death certificates with mention of stroke in the United States as a proxy measure of the incidence of dying from AP or choking among patients with stroke.
We used multiple-cause mortality data for the years 2001 to 2010 to identify death certificates with mention of stroke (International Classification of Diseases, Tenth Revision code I60-I69), AP (International Classification of Diseases, Tenth Revision code J69), and choking (International Classification of Diseases, Tenth Revision code W78-W80) for analysis.
Of 2 424 379 death certificates with mention of stroke in the United States between 2001 and 2010, 5.1% (n=124 503) reported AP as a cause of death, and 1.5% (n=36 997) reported choking as a cause of death. However, if we confined the analysis to autopsy-confirmed cases, the frequency decreased to 1.3% (555/42 732) and 1.3% (541/42 732), respectively. The adjusted odds ratios of reporting AP or choking as a cause of death were higher among men, increased with age, and were higher among decedents who died in a nursing home/long-term care.
The estimated incidence of dying from AP and choking among patients who died with stroke was 5% (12 000 deaths per year) and 1% (3700 deaths per year) according to information reported on death certificates. Efforts are needed to reduce the number of deaths from these 2 preventable complications.
目前尚不清楚美国每年有多少因致命性肺部并发症(如吸入性肺炎[AP]和窒息)而死于中风的患者。本研究旨在通过使用美国死亡证明中提及中风的情况来确定报告 AP 或窒息作为死亡原因的频率,以此作为中风患者死于 AP 或窒息的发病率的替代指标。
我们使用 2001 年至 2010 年的多病因死亡率数据,确定美国有提及中风(国际疾病分类,第十版编码 I60-I69)、AP(国际疾病分类,第十版编码 J69)和窒息(国际疾病分类,第十版编码 W78-W80)的死亡证明,进行分析。
在 2001 年至 2010 年间,美国有 2424379 份提及中风的死亡证明,其中 5.1%(n=124503)报告 AP 为死亡原因,1.5%(n=36997)报告窒息为死亡原因。但是,如果我们将分析仅限于尸检证实的病例,频率分别降至 1.3%(555/42732)和 1.3%(541/42732)。报告 AP 或窒息为死亡原因的调整后比值比在男性中较高,随年龄增长而增加,在在疗养院/长期护理机构死亡的死者中更高。
根据死亡证明上报告的信息,死于中风的患者死于 AP 和窒息的估计发病率为 5%(每年约 12000 例死亡)和 1%(每年约 3700 例死亡)。需要努力减少这两种可预防并发症导致的死亡人数。