Sahle Adeba Tadesse, Mekonen Hussen, Alemu Tsion, Alate Tamrat, Melis Tamirat
Department of Nursing, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.
School of Nursing and Midwifery, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.
SAGE Open Med. 2022 Jul 30;10:20503121221112483. doi: 10.1177/20503121221112483. eCollection 2022.
In Africa, there is up to 316 per 100,000 annual incidence rate of stroke, a prevalence of up to 1460 per 100,000, and a 3-year mortality rate higher than 80%. The incidence of stroke mortality in Ethiopia is 19.2%. Stroke is a major cause of disability and death worldwide. Early mortality in-hospital and deprived functional outcomes are common in acute stroke. This study aims to assess survival status and predictors of mortality among adult stroke patients.
Institution-based retrospective cohort was conducted on patients who were admitted to Saint Paul's Hospital Millennium Medical College. A simple random sampling technique was used. Bivariate and multivariable cox regression analysis were used to identify predictors of stroke mortality. For multivariable cox regression analysis statistically, significance was declared at -value <0.05 and 95% CI.
A total of 251 adult stroke patient charts were included in the study. The overall Kaplan-Meier estimate showed that the probability of in-hospital stroke patients' survival on the 41st day was nearly 50%. In this study, 77 (30.7%) of the study participants died. Decreased Glasgow Coma Scale (GCS) with adjusted hazard ratio (AHR) 4.26 (95% CI: 2.25-8.07) and -value ⩽ 0.01 and presence of pneumonia with AHR 3.05 (95% CI: 1.29-7.21) and -value ⩽ 0.01 are the predictor of mortality.
The probability of survival relatively falls as follow-up time increases. The overall incidence of mortality among adult stroke patients was high. The decreased GCS and the presence of pneumonia are predictors of mortality among adult stroke patients.
在非洲,中风的年发病率高达每10万人316例,患病率高达每10万人1460例,3年死亡率高于80%。埃塞俄比亚中风死亡率为19.2%。中风是全球致残和死亡的主要原因。急性中风患者住院早期死亡和功能预后不良很常见。本研究旨在评估成年中风患者的生存状况及死亡预测因素。
对入住圣保罗医院千禧医学院的患者进行基于机构的回顾性队列研究。采用简单随机抽样技术。使用双变量和多变量cox回归分析来确定中风死亡的预测因素。对于多变量cox回归分析,当P值<0.05和95%可信区间时具有统计学意义。
本研究共纳入251份成年中风患者病历。总体Kaplan-Meier估计显示,住院中风患者在第41天存活的概率接近50%。在本研究中,77名(30.7%)研究参与者死亡。格拉斯哥昏迷量表(GCS)降低,调整后危险比(AHR)为4.26(95%可信区间:2.25 - 8.07),P值⩽0.01,以及存在肺炎,AHR为3.05(95%可信区间:1.29 - 7.21),P值⩽0.01是死亡的预测因素。
随着随访时间的增加,存活概率相对下降。成年中风患者的总体死亡率很高。GCS降低和存在肺炎是成年中风患者死亡的预测因素。