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非流行地区匐行性脉络膜炎作为结核病的标志物。

Serpiginous-like choroiditis as a marker for tuberculosis in a non-endemic area.

机构信息

Manchester Royal Eye Hospital, Oxford Road, Manchester M13 9WL, UK.

出版信息

Br J Ophthalmol. 2013 May;97(5):644-7. doi: 10.1136/bjophthalmol-2012-302918. Epub 2013 Feb 28.

Abstract

AIM

To describe the increasing incidence of multifocal outer retinal and inner choroidal inflammation as a marker for intraocular tuberculosis in the UK, a non-endemic area.

PATIENTS AND METHODS

Retrospective case series.

RESULTS

14 patients presented with serpiginous-like choroiditis over 10 years (seven within the last 2 years). Seven of 14 patients showed evidence of exposure to tuberculosis and received antituberculous treatment. 17 of 23 eyes showed stable or improved visual acuity. All with decreased acuity had direct macular involvement at presentation.

CONCLUSIONS

Multifocal outer retinal and inner choroidal inflammation is a marker for intraocular tuberculosis of increasing importance, even in a non-endemic area. Originally described as 'serpiginous-like choroiditis', the lesions are multifocal, irregular in shape, very numerous, widespread, often asymmetrical and often demonstrating both active and resolved lesions simultaneously. Active lesions show contiguous extension. We recommend that every patient with SLC should undergo testing for previous exposure to tuberculosis, and undergo antituberculous treatment if lesions are progressive and sight-threatening.

摘要

目的

描述多发的外层视网膜和内层脉络膜炎症作为英国(非地方性流行区)眼内结核的标志不断增加的发病率。

患者和方法

回顾性病例系列。

结果

14 例患者在 10 年内出现匐行性脉络膜炎(最近 2 年内 7 例)。14 例患者中有 7 例有结核病接触史,并接受了抗结核治疗。23 只眼中的 17 只视力稳定或改善。所有视力下降的患者在就诊时均有直接的黄斑受累。

结论

多发的外层视网膜和内层脉络膜炎症是眼内结核的一个越来越重要的标志,即使在非地方性流行区也是如此。最初被描述为“匐行性脉络膜炎”,病变呈多发性、形状不规则、非常多、广泛分布,常不对称,常同时显示活动和已解决的病变。活动病变呈连续扩展。我们建议,每例 SLC 患者都应进行结核病既往接触检测,如果病变进展且威胁视力,应进行抗结核治疗。

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