Sujata Jetley, S Rana, Sabina Khan, Mj Hassan, Jairajpuri Zeeba Shamim
Associate Professor, Department of Pathology, HIMSR , New Delhi, India .
J Clin Diagn Res. 2013 Jan;7(1):85-8. doi: 10.7860/JCDR/2012/5001.2677. Epub 2012 Oct 31.
Gall bladder carcinoma accounts for 98% of all the gall bladder malignancies and it is the sixth most common malignancy of the gastrointestinal tract worldwide. The incidence of incidental gall bladder carcinoma which is diagnosed during or after a laparoscopic cholecystectomy is reported to be around 0.19-3.3% in the literature.
This study was aimed at detecting the incidence of gall bladder carcinomas which were diagnosed incidentally during or after laparoscopic cholecystectomies which were done for gall stone disease and cholecystitis.
We analyzed the medical records of patients with symptomatic gallstone disease and acute or chronic cholecystitis, who underwent laparoscopic cholecystectomies at the Hakeem Abdul Hameed Centenary Hospital during the period from January 2007 to June 2012.
A total of 622 laparoscopic cholecystectomies were performed at our institute during the study period of five and a half years. In 6 (0.96%) cases, incidental carcinomas of the gallbladder were discovered.
A laparoscopic cholecystectomy which is performed for benign gall bladder disease rarely results in a diagnosis of unexpected gallbladder cancer. The microscopic examination of the specimens, with special attention to the depth of invasion, range of the mucosal spread and the lymphovascular involvement, is critical in diagnosing the incidental malignancies as well as for the subsequent management of the cases.
胆囊癌占所有胆囊恶性肿瘤的98%，是全球第六大常见的胃肠道恶性肿瘤。据文献报道，在腹腔镜胆囊切除术期间或之后诊断出的意外胆囊癌的发生率约为0.19 - 3.3%。
本研究旨在检测因胆结石疾病和胆囊炎而进行的腹腔镜胆囊切除术期间或之后意外诊断出的胆囊癌的发生率。
我们分析了2007年1月至2012年6月期间在哈基姆·阿卜杜勒·哈米德百年医院接受腹腔镜胆囊切除术的有症状胆结石疾病和急性或慢性胆囊炎患者的病历。
在我们研究所为期五年半的研究期间，共进行了622例腹腔镜胆囊切除术。其中6例（0.96%）发现了意外的胆囊癌。
因良性胆囊疾病进行的腹腔镜胆囊切除术很少导致意外胆囊癌的诊断。对标本进行显微镜检查，特别注意浸润深度、黏膜扩散范围和淋巴管受累情况，对于诊断意外恶性肿瘤以及后续病例管理至关重要。
