Department of Surgery, Universal College of Medical Sciences, Bhairahawha, Nepal.
Department of Pathology, Universal College of Medical Sciences, Bhairahawha, Nepal.
J Nepal Health Res Counc. 2020 Nov 14;18(3):547-550. doi: 10.33314/jnhrc.v18i3.1974.
Gallbladder cancer is the most common biliary tract cancer. Incidence rate of gall bladder cancer varies worldwide. Most of the patient with gall bladder cancer remained asymptomatic until late. Preoperative early diagnosis of carcinoma of gallbladder is rare, occurring in fewer than 20% of patients. Role of routine histopathology for cholecystectomy specimen is debatable. Aim of this study is to find the incidence of incidental gall bladder cancer and determine whether routine histopathology of cholecystectomy specimen is required or not.
This is a retrospective descriptive study carried out in Universal College of Medical Sciences, Bhairahawha, Nepal. Histopathology reports of all patients who had undergone cholecystectomies from June 2014 to September 2018 were reviewed. Patients' information regarding inpatient number, age, sex, year of diagnosis, preoperative diagnosis, intraoperative findings, histopathology report and pathological staging were recorded. Data were entered and analyzed using Microsoft Excel version 14.
Total of 418 routine cholecystectomies were performed during this period. Seven cases of incidental gall bladder cancer were diagnosed. None of the patients had preoperative suspicion for malignancy. One patient had intraoperative suspicion of lesion.
Incidence of incidental gallbladder cancer is 1.67%. It is recommended that routine histopathology of cholecystectomy specimen should be sent for early diagnosis and improve survival of patient with gall bladder cancer.
胆囊癌是最常见的胆道系统恶性肿瘤。胆囊癌的发病率在全球范围内存在差异。大多数胆囊癌患者在晚期才出现症状。术前早期诊断胆囊癌较为罕见，少于 20%的患者会出现这种情况。胆囊切除术标本的常规组织病理学检查的作用存在争议。本研究旨在探讨胆囊意外癌的发生率，并确定是否需要对胆囊切除术标本进行常规组织病理学检查。
这是在尼泊尔巴伊拉瓦哈的环球医学院进行的回顾性描述性研究。回顾了 2014 年 6 月至 2018 年 9 月期间所有接受胆囊切除术的患者的组织病理学报告。记录了患者的住院号、年龄、性别、诊断年份、术前诊断、术中发现、组织病理学报告和病理分期等信息。使用 Microsoft Excel 版本 14 输入和分析数据。
在此期间共进行了 418 例常规胆囊切除术。诊断出 7 例意外胆囊癌。没有患者术前怀疑恶性肿瘤。1 例患者术中怀疑有病变。
意外胆囊癌的发生率为 1.67%。建议对胆囊切除术标本进行常规组织病理学检查，以便早期诊断和提高胆囊癌患者的生存率。
