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非霍奇金淋巴瘤患者的肾脏受累情况:23例临床及病理特征

Renal involvement in patients with non-Hodgkin's lymphoma: clinical and pathological features in 23 cases.

作者信息

Richards M A, Mootoosamy I, Reznek R H, Webb J A, Lister T A

机构信息

ICRF Department of Medical Oncology, St. Bartholomew's Hospital, London, U.K.

出版信息

Hematol Oncol. 1990 Mar-Apr;8(2):105-10. doi: 10.1002/hon.2900080206.

DOI:10.1002/hon.2900080206
PMID:2344997
Abstract

Twenty-three cases of renal or perirenal involvement by non-Hodgkin's lymphoma were identified from a retrospective review of computed tomography (CT) scans performed on patients at St Bartholomew's Hospital over an 8-year period. The histology, clinical features and survival of these patients were examined. Eighteen of the 23 patients had high grade histological subtypes according to the Kiel classification. The majority of cases were identified from scans performed at the time of presentation. In nine cases renal lymphoma was observed in the absence of detectable retroperitoneal lymphadenopathy. Staging was rarely altered by the finding of renal lymphoma as 21 of the 23 patients had involvement of other extranodal sites in addition to the kidney. Survival did not appear to be adversely affected by the presence of renal lymphoma at the time of initial diagnosis. During the same period no cases of renal involvement were identified in patients with Hodgkin's disease, although one patient had perirenal involvement.

摘要

通过对圣巴塞洛缪医院患者在8年期间进行的计算机断层扫描(CT)进行回顾性分析,确定了23例非霍奇金淋巴瘤累及肾脏或肾周的病例。对这些患者的组织学、临床特征和生存率进行了检查。根据基尔分类,23例患者中有18例为高级别组织学亚型。大多数病例是在初诊时进行的扫描中发现的。在9例病例中,在未检测到腹膜后淋巴结肿大的情况下观察到肾淋巴瘤。由于23例患者中有21例除肾脏外还累及其他结外部位,肾淋巴瘤的发现很少改变分期。初始诊断时肾淋巴瘤的存在似乎并未对生存率产生不利影响。在同一时期,霍奇金病患者中未发现肾脏受累病例,尽管有1例患者肾周受累。

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