Prabhakar D, Gupta K L, Gochhait D, Nada R, Varma S C, Kumar V, Rathi M, Kohli H S, Sakhuja V, Ramachandran R
Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Nephrol. 2015 Jan-Feb;25(1):43-5. doi: 10.4103/0971-4065.140723.
A 60-year male was admitted with advanced renal failure and bilaterally enlarged kidneys. Kidney biopsy revealed diffuse interstitial infiltration by CD20 + lymphomatous cells suggestive of diffuse large B-cell, non-Hodgkin's lymphoma. Bone marrow examination was negative for malignant cells. Positron emission tomography-computed tomography showed uniformly diffuse and avid flurodeoxy glucose uptake in both kidneys, multiple hypodense areas of both lobes of liver, and axial and appendicular skeleton. Patient was treated with rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine and prednisolone, became afebrile and serum creatinine normalized.
一名60岁男性因晚期肾衰竭和双侧肾脏肿大入院。肾脏活检显示CD20 + 淋巴瘤细胞弥漫性间质浸润，提示弥漫性大B细胞非霍奇金淋巴瘤。骨髓检查未发现恶性细胞。正电子发射断层扫描-计算机断层扫描显示双侧肾脏、肝脏两叶多个低密度区以及轴骨和四肢骨骼均有均匀弥漫性且强烈的氟脱氧葡萄糖摄取。患者接受了利妥昔单抗、环磷酰胺、羟基柔红霉素、长春新碱和泼尼松龙治疗，发热消退，血清肌酐恢复正常。
