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Reprod Health. 2010 May 12;7:7. doi: 10.1186/1742-4755-7-7.
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4
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Hum Reprod. 2007 Jun;22(6):1506-12. doi: 10.1093/humrep/dem046. Epub 2007 Mar 21.
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Fertil Steril. 2006 Feb;85(2):285-9. doi: 10.1016/j.fertnstert.2005.07.1326.
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Unmet fertility expectations and the perception of fertility problems in a Malawian village.
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Human immunodeficiency virus and infertility treatment.
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感染逆转录病毒(HIV)呈阳性和阴性的不孕女性的子宫输卵管造影输卵管异常情况

Hysterosalpingographic Tubal Abnormalities in Retroviral (HIV) Positive and Negative Infertile Females.

作者信息

Adegoke Aremu Ademola, Anthony Eka, Olumide Alao B, Folake Olajide, Idowu Ajayi A

机构信息

Department of Radiology, Ladoke Akintola University of Technology Ogbomoso Oyo State , Nigeria .

出版信息

J Clin Diagn Res. 2013 Jan;7(1):35-8. doi: 10.7860/JCDR/2012/4938.2664. Epub 2013 Jan 1.

DOI:10.7860/JCDR/2012/4938.2664
PMID:23450063
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3576745/
Abstract

BACKGROUND

HIV and infertility are associated in several ways and the improved treatment options which are available for HIV patients have improved their health, increased their reproductive years and subsequently, their desire to procreate.

OBJECTIVE

The objective was to compare the findings on hysterosalpingography in HIV positive and negative infertile females.

STUDY DESIGN

All the 5250 patients who were referred to the radiodiagnosis unit of the centre in 2011, were counselled about the study, but only the two thousand and two hundred females who gave their consents had their retroviral status determined and were included in this study. Their sociodemographic histories were acquired with the aid of a structured questionnaire and their hysterosalpingography studies were reported by a radiologist.

RESULTS

Most of the patients (54.5%) were within the age group of 31-40 years, they were mainly nullparous (76.8%) and a past history of induced abortions was statistically significant in the HIV positive patients compared to HIV negative patients. Also, the uterine synechiae were significantly higher in the HIV positive than the HIV negative patients (26.5% and 9.6% respectively). Tubal abnormalities were seen in 52% and 26% of the positive and negative individuals respectively, with hydrosalpinges being the commonest pathology in the HIV positive patients and distal occlusion being the commonest in the HIV negative patients.

CONCLUSION

Tubal infertility is the commonest cause of the infertility in the HIV positive individuals and the commonest tubal pathology is hydrosalpinges as compared to distal tubal occlusion in the HIV negative patients .There is a need to not only research further into the treatment and other options for the patients with tubal infertility, but also to make them available and affordable to provide succour to this group of patients, no matter what their retroviral status is.

摘要

背景

HIV与不孕在多个方面存在关联,而针对HIV患者的治疗选择不断改善,这提升了他们的健康水平,延长了其生殖年限,进而增强了他们的生育意愿。

目的

比较HIV阳性和阴性不孕女性的子宫输卵管造影检查结果。

研究设计

2011年转诊至该中心放射诊断科的5250例患者均接受了关于该研究的咨询,但只有两千两百名同意参与的女性进行了逆转录病毒状态检测并纳入本研究。借助结构化问卷收集她们的社会人口学病史,子宫输卵管造影检查结果由一名放射科医生报告。

结果

大多数患者(54.5%)年龄在31 - 40岁之间,主要为未生育过(76.8%),与HIV阴性患者相比,HIV阳性患者既往人工流产史具有统计学意义。此外,HIV阳性患者的子宫粘连明显高于HIV阴性患者(分别为26.5%和9.6%)。阳性和阴性个体中输卵管异常分别见于52%和26%,输卵管积水是HIV阳性患者中最常见的病变,而远端阻塞是HIV阴性患者中最常见的病变。

结论

输卵管性不孕是HIV阳性个体不孕的最常见原因,与HIV阴性患者的远端输卵管阻塞相比,最常见的输卵管病变是输卵管积水。不仅需要进一步研究输卵管性不孕患者的治疗及其他选择,还需使其可得且价格可承受,以便为这群患者提供帮助,无论其逆转录病毒状态如何。