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资源受限地区剖宫产患者脊髓麻醉给药时侧卧位与坐位对产妇血流动力学变异性及低血压发生时间的影响:一项前瞻性观察队列研究

Impact of being lateral and sitting position for spinal anesthesia administration on maternal hemodynamic variability and the timing of hypotension among cesarean section patients in a resource-constrained area: a prospective observational cohort study.

作者信息

Samuel Sintayehu, Kasahun Blen, Demeke Tsegaye, Reshad Seleman, Shemsu Nesredin, Kedir Abdulkadir, Achule Astemamagn, Mamo Temesgen, Dendir Getahun, Genetu Sinishaw, Wolde Yisehak

机构信息

Department of Anesthesia, Wachemo University, Hossaena, Ethiopia.

School of Anesthesia, Wolaita Sodo University, Sodo, Ethiopia.

出版信息

Ann Med Surg (Lond). 2025 Jan 9;87(1):62-69. doi: 10.1097/MS9.0000000000002754. eCollection 2025 Jan.

Abstract

BACKGROUND

Type of anesthesia used for cesarean section can be general, spinal, or epidural. However, peripheral nerve blocks, such as the lower and upper extremity nerve blocks, can be referred to as other types of anesthesia. Spinal anesthesia is the most frequently used method because of its ease, dependability, and rapidity in attaining proper anesthesia. The purpose of this study was to determine the effects of spinal anesthesia induction position on maternal hemodynamics and the timing of hypotension.

METHOD

A prospective observational cohort study design was employed. A simple random sampling technique was used. A total of 190 patients received spinal anesthesia, with 95 in the lateral and 95 in the sitting position in each group. The data were entered into Epi Data version 4.6 and then exported to SPSS version 26 for analysis. Independent sample -tests and chi-square ( ) tests were performed. Kaplan-Meier survival analysis and log-rank test were used and value ≤0.05 considered significant.

RESULTS

The overall incidence rates of hypotension in the lateral and sitting groups were 54.6% [95% CI, 52.3-72.1] and 73.8% [95% CI, 69.8-87.2], respectively ( = 0.025). The timing of first hypotension was 8.86 minute [95% CI, 8.690-13.272] and 15.75 minute [95% CI, 14.569-19.372] ( = 0.001) for sitting and lateral, respectively.

CONCLUSION AND RECOMMENDATION

In this study, we found a significant difference between the lateral and sitting groups with different measurement parameters, such as blood pressure, intraoperative adverse events, and onset of hypotension. The incidence of hypotension, intraoperative adverse effects of spinal anesthesia, and fluid consumption were lower in the lateral groups. Nonetheless, instead of being technically challenging during spinal anesthesia induction, the lateral position results in better hemodynamics and onset of hypotension than in the sitting posture.

摘要

背景

剖宫产所用的麻醉方式可以是全身麻醉、脊髓麻醉或硬膜外麻醉。然而,外周神经阻滞,如下肢和上肢神经阻滞,可被视为其他类型的麻醉。脊髓麻醉因其操作简便、可靠且能迅速达到适当的麻醉效果而成为最常用的方法。本研究的目的是确定脊髓麻醉诱导体位对产妇血流动力学和低血压发生时间的影响。

方法

采用前瞻性观察队列研究设计。使用简单随机抽样技术。共有190例患者接受脊髓麻醉,每组95例,分别处于侧卧位和坐位。数据录入Epi Data 4.6版本,然后导出到SPSS 26版本进行分析。进行独立样本t检验和卡方检验。采用Kaplan-Meier生存分析和对数秩检验,P值≤0.05认为具有统计学意义。

结果

侧卧位组和坐位组低血压的总体发生率分别为54.6%[95%CI,52.3 - 72.1]和73.8%[95%CI,69.8 - 87.2](P = 0.025)。坐位组和侧卧位组首次出现低血压的时间分别为8.86分钟[95%CI,8.690 - 13.272]和15.75分钟[95%CI,14.569 - 19.372](P = 0.001)。

结论与建议

在本研究中,我们发现侧卧位组和坐位组在不同测量参数(如血压、术中不良事件和低血压发作)方面存在显著差异。侧卧位组低血压发生率、脊髓麻醉的术中不良反应和液体消耗量较低。尽管如此,侧卧位在脊髓麻醉诱导过程中并非技术上具有挑战性,而且与坐位相比,其血流动力学更好,低血压发作时间更合适。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83cf/11918601/a8d368cbd4b9/ms9-87-062-g001.jpg

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