接受抗逆转录病毒治疗且病毒载量不可检测的HIV阳性个体中，阿扎那韦血浆水平与肾功能之间的关联。 - Suppr

Association between atazanavir plasma levels and renal function in HIV-positive individuals on antiretroviral therapy with undetectable viral load.

作者信息

Luz Ana Júlia, Poeta Júlia, Linden Rafael, Antunes Marina Venzon, Caminha Luiza Isola, Callegari-Jacques Sidia Maria, Sprinz Eduardo

出版信息

Int J Antimicrob Agents. 2013 May;41(5):497-8. doi: 10.1016/j.ijantimicag.2013.01.013. Epub 2013 Feb 28.

DOI:10.1016/j.ijantimicag.2013.01.013

PMID:23453620

Abstract

摘要

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Association between atazanavir plasma levels and renal function in HIV-positive individuals on antiretroviral therapy with undetectable viral load.接受抗逆转录病毒治疗且病毒载量不可检测的HIV阳性个体中，阿扎那韦血浆水平与肾功能之间的关联。

Int J Antimicrob Agents. 2013 May;41(5):497-8. doi: 10.1016/j.ijantimicag.2013.01.013. Epub 2013 Feb 28.

Efficacy and safety of ritonavir-boosted dual protease inhibitor therapy in antiretroviral-naive HIV-1-infected patients: the 2IP ANRS 127 study.利托那韦增强型双蛋白酶抑制剂疗法在初治HIV-1感染患者中的疗效和安全性：2IP ANRS 127研究

J Antimicrob Chemother. 2009 Jul;64(1):118-25. doi: 10.1093/jac/dkp146. Epub 2009 May 6.

Outcomes of switch to atazanavir-containing combination antiretroviral therapy in HIV-1-infected patients with hyperlipidemia.在患有高血脂的 HIV-1 感染患者中，转换为含阿扎那韦的联合抗逆转录病毒治疗的结果。

J Microbiol Immunol Infect. 2011 Aug;44(4):258-64. doi: 10.1016/j.jmii.2010.08.003. Epub 2011 Jan 20.

High incidence of renal stones among HIV-infected patients on ritonavir-boosted atazanavir than in those receiving other protease inhibitor-containing antiretroviral therapy.在接受利托那韦增效阿扎那韦治疗的 HIV 感染患者中，肾结石的发病率高于接受其他含蛋白酶抑制剂的抗逆转录病毒治疗的患者。

Clin Infect Dis. 2012 Nov;55(9):1262-9. doi: 10.1093/cid/cis621. Epub 2012 Jul 19.

Efficacy and safety of atazanavir-based highly active antiretroviral therapy in patients with virologic suppression switched from a stable, boosted or unboosted protease inhibitor treatment regimen: the SWAN Study (AI424-097) 48-week results.基于阿扎那韦的高效抗逆转录病毒疗法在从稳定的、加用或未加用增效剂的蛋白酶抑制剂治疗方案转换过来且病毒学得到抑制的患者中的疗效和安全性：SWAN研究（AI424 - 097）48周结果

Clin Infect Dis. 2007 Jun 1;44(11):1484-92. doi: 10.1086/517497. Epub 2007 Apr 25.

[Highly effective and tolerable protease inhibitor. New trump card against HIV].[高效且耐受性良好的蛋白酶抑制剂。对抗艾滋病病毒的新王牌]

MMW Fortschr Med. 2003 Jan 16;145(1-2):55.

HIV type 1 viral encephalitis after development of viral resistance to plasma suppressive antiretroviral therapy.在对血浆抑制性抗逆转录病毒疗法产生病毒耐药性后出现的1型人类免疫缺陷病毒病毒性脑炎

AIDS Res Hum Retroviruses. 2012 Jan;28(1):83-6. doi: 10.1089/AID.2011.0020. Epub 2011 May 21.

Higher CNS penetration-effectiveness of long-term combination antiretroviral therapy is associated with better HIV-1 viral suppression in cerebrospinal fluid.长期联合抗逆转录病毒疗法对中枢神经系统的穿透力和有效性与脑脊液中 HIV-1 病毒抑制效果更好相关。

J Acquir Immune Defic Syndr. 2013 Jan 1;62(1):28-35. doi: 10.1097/QAI.0b013e318274e2b0.

Atazanavir: new indication. First-line treatment: fewer gastrointestinal disorders but more cases of jaundice and a risk of torsades de pointes.

Prescrire Int. 2009 Jun;18(101):104.

Raltegravir and unboosted atazanavir dual therapy in virologically suppressed antiretroviral treatment-experienced HIV patients.拉替拉韦与未联用增效剂的阿扎那韦双重疗法用于病毒学抑制的、有抗逆转录病毒治疗经验的HIV患者。

Antivir Ther. 2010;15(7):1035-8. doi: 10.3851/IMP1647.

引用本文的文献

Renal effects of non-tenofovir antiretroviral therapy in patients living with HIV.非替诺福韦抗逆转录病毒疗法对HIV感染者肾脏的影响。

Drugs Context. 2018 Mar 21;7:212519. doi: 10.7573/dic.212519. eCollection 2018.

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Association between atazanavir plasma levels and renal function in HIV-positive individuals on antiretroviral therapy with undetectable viral load.

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