Clínica Imagem, Florianopolis, Brazil.
J Neurol Sci. 2013 Apr 15;327(1-2):61-2. doi: 10.1016/j.jns.2013.01.032. Epub 2013 Feb 28.
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) has been described as a clinically and radiologically distinct pontine-predominant encephalomyelitis with a favorable response to high dose corticosteroids and usually requiring chronic immunosuppresive therapy. Brain magnetic resonance imaging (MRI) reveals a characteristic pattern of punctate and curvilinear enhancement lesions in the pons extending variably to surrounding areas. We herein describe such imaging findings in a patient with a definite diagnosis of relapsing-remitting multiple sclerosis (MS).
慢性淋巴细胞性炎症伴桥脑血管周围强化对类固醇有反应(CLIPPERS)已被描述为一种临床上和放射学上有明显区别的桥脑为主的脑脊髓炎,对大剂量皮质类固醇有良好的反应,通常需要慢性免疫抑制治疗。脑磁共振成像(MRI)显示出特征性的点状和曲线状强化病变模式,在桥脑延伸至周围区域。我们在此描述了一位明确诊断为复发缓解型多发性硬化症(MS)的患者的这种影像学发现。