Forrester T E, Grell G A, Bennett F, Bernard W, Gordon B
Tropical Metabolism Research Unit, University of the West Indies, Mona, Kingston.
J Hum Hypertens. 1990 Feb;4(1):25-30.
Blood pressure and leucocyte sodium content were measured in black Jamaican patients with pre-eclampsia and pregnant controls. Similar measurements were made in a group of mothers who had pre-eclampsia 36-38 weeks previously and their controls. An increase in cell sodium accompanied the high blood pressure in patients with pre-eclampsia. There was also some elevation of both blood pressure and cell sodium in patients who had had pre-eclampsia 36-38 weeks previously. These findings suggest that disturbances of cellular electrolytes continue into the post-partum period. Changes in intracellular sodium may be important in the pathogenesis of pre-eclampsia as they parallel the increase in blood pressure levels.
对患有先兆子痫的牙买加黑人患者和怀孕对照组进行了血压和白细胞钠含量的测量。对一组在36 - 38周前患有先兆子痫的母亲及其对照组进行了类似测量。先兆子痫患者中,细胞内钠增加伴随高血压出现。在36 - 38周前患有先兆子痫的患者中,血压和细胞内钠也有一定程度升高。这些发现表明,细胞电解质紊乱会持续到产后阶段。细胞内钠的变化在先兆子痫发病机制中可能很重要,因为它们与血压水平升高同步。