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[利用电刺激预防运动功能减退期间肌肉变化的发生]

[Use of electric stimulation to prevent the development of muscle changes during hypokinesia].

作者信息

Portugalov V V, Il'ina-Kakueva E I, Starostin V I

出版信息

Kosm Biol Aviakosm Med. 1975 Jan-Feb;9(1):9-13.

PMID:234552
Abstract

An attempt was made to use electric stimulation of antigravity muscles of hind limbs of rats exposed to a 15 and 30 day hypokinesia as a method for preventing structural and metabolic disorders that develop in the muscular tissue during a diminished motor activity. The electric stimulation was carried out using the Bion device with a frequency-amplitude modulation. The impulses of an amplitude of 0.7-1 msec and a frequency of 100 to 130 Hz were modulated with a frequency of 0.5 Hz. During the first experimental days the electric stimulation was 5 to 7 min and by the end of the first week it reached 30 min. Throughout the first week the voltage grew from 6-7 to 20 V. Electric stimulation was applied 5 times a week. The favourable effect of the electric stimulation was demonstrated in 4 out of 12 animals during every experimental run. It is suggested that a higher percentage of the protective effect of the method can be achieved with the stimulation ensuring a more intensive influence on the deeply located muscles.

摘要

尝试将电刺激应用于经历15天和30天运动不足的大鼠后肢抗重力肌肉,以此作为一种预防因运动活动减少而在肌肉组织中出现的结构和代谢紊乱的方法。使用具有频率 - 幅度调制功能的Bion设备进行电刺激。幅度为0.7 - 1毫秒、频率为100至130赫兹的脉冲以0.5赫兹的频率进行调制。在实验的最初几天,电刺激持续5至7分钟,到第一周结束时达到30分钟。在第一周内,电压从6 - 7伏升至20伏。每周进行5次电刺激。在每次实验过程中,12只动物中有4只显示出电刺激的有利效果。有人认为,通过确保对深部肌肉产生更强烈影响的刺激,该方法的保护效果百分比可能会更高。

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