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细针穿刺细胞学检查中肾上腺病变的谱系

Spectrum of adrenal lesions on fine needle aspiration cytology.

作者信息

Rana Chanchal, Krishnani Narendra, Kumari Niraj

机构信息

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

Indian J Pathol Microbiol. 2012 Oct-Dec;55(4):461-6. doi: 10.4103/0377-4929.107781.

DOI:10.4103/0377-4929.107781
PMID:23455780
Abstract

BACKGROUND

Fine needle aspiration (FNA) cytology of adrenal gland is not a commonly performed technique and is limited primarily to tertiary care centers. However, it is a sensitive and specific procedure in the workup of patients with adrenal gland's mass lesions. Though cytomorphological features for various lesions have been described, there are a limited number of studies in cytologic literature.

AIMS

We report our 7 years of experience in FNAC of adrenal lesions. We have not only described the cytomorphological details of different lesions, but also tried to discuss the various diagnostic difficulties encountered during reporting of adrenal fine needle aspirations.

MATERIALS AND METHODS

All ultrasound-guided percutaneous aspirations of adrenal gland received in the department between the years 2002 and 2009 were reviewed. There were a total of 52 FNA samples of adrenal masses from 35 patients in 7 years. The lesions were categorized as non-neoplastic and neoplastic categories. Neoplastic lesions were further divided into benign and malignant lesions.

RESULTS

In our study, FNA proved to be 100% specific for diagnosing malignant lesions. The overall inadequacy rate was 11.4% with no major complications of the procedure. A wide variety of non-neoplastic as well as neoplastic lesions were identified.

摘要

背景

肾上腺细针穿刺抽吸(FNA)细胞学检查并非一种常用技术,主要限于三级医疗中心开展。然而,在肾上腺肿块性病变患者的检查中,它是一种敏感且特异的方法。尽管已经描述了各种病变的细胞形态学特征,但细胞学文献中的相关研究数量有限。

目的

我们报告了7年来肾上腺病变细针穿刺抽吸活检(FNAC)的经验。我们不仅描述了不同病变的细胞形态学细节,还试图讨论在报告肾上腺细针穿刺抽吸结果时遇到的各种诊断困难。

材料与方法

回顾了2002年至2009年期间本科室接收的所有超声引导下肾上腺经皮穿刺抽吸样本。7年间共有来自35例患者的52份肾上腺肿块FNA样本。病变分为非肿瘤性和肿瘤性类别。肿瘤性病变进一步分为良性和恶性病变。

结果

在我们的研究中,FNA在诊断恶性病变方面特异性为100%。总体不满意率为11.4%,该操作无重大并发症。识别出了多种非肿瘤性和肿瘤性病变。

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