Das Chhanda, Sengupta Moumita, Mukhopadhyay Madhumita, Saha Ashis Kumar
Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
Department of Surgery, B.S Medical College, Bankura, West Bengal, India.
Indian J Med Paediatr Oncol. 2014 Jan;35(1):60-5. doi: 10.4103/0971-5851.133723.
Fine-needle aspiration (FNA) is increasing in popularity as a means of diagnosing mass lesions in retroperitoneal area. With use of radiologic guidance for needle placement, this technique is an effective way to obtain diagnostic material.
The aims of the study were (1) to establish the validity and reliability of fine needle aspiration cytology in preoperative diagnosis of retroperitoneal tumor, and (2) to compare the significance of cytological diagnosis with histopathological report.
A prospective, cross-sectional hospital-based study.
A prospective, cross-sectional study was designed on 45 cases of clinically and radiologically diagnosed retroperitoneal tumor in a tertiary care hospital. Computerized tomography (CT)-guided percutaneous FNA was performed and cytology smears were stained with May-Grünwald-Giemsa stain and conventional Papanicolaou (Pap) stain. Smears were broadly categorized into unsatisfactory, benign, suspicious of malignancy and malignant lesion. The cytological diagnosis was compared with subsequent histopathology report.
Positive and negative predictive values, diagnostic accuracy, chi-square test and others.
The total number of cases studied was 45, which include both epithelial tumors and mesenchymal tumors. Age group varied from 15 to 70 years. The overall sensitivity in our study to diagnose benign and malignant tumors by FNA cytology is 86% and the specificity is 96% with positive and negative predictive value of 86% and 96%, respectively. Diagnostic accuracy was 93.55% with high statistical significance (P < 0.001).
FNA cytology is a simple, fast, reliable and less expensive method for diagnosis of various retroperitoneal neoplasms.
细针穿刺抽吸术（FNA）作为诊断腹膜后区域肿块性病变的一种手段，越来越受到欢迎。借助放射学引导进行针的放置，该技术是获取诊断材料的有效方法。
本研究的目的是（1）确定细针穿刺抽吸细胞学在腹膜后肿瘤术前诊断中的有效性和可靠性，以及（2）比较细胞学诊断与组织病理学报告的意义。
一项基于医院的前瞻性横断面研究。
在一家三级护理医院对45例临床和放射学诊断为腹膜后肿瘤的患者进行了一项前瞻性横断面研究。采用计算机断层扫描（CT）引导下经皮FNA，细胞学涂片用May-Grünwald-Giemsa染色和传统巴氏（Pap）染色。涂片大致分为不满意、良性、可疑恶性和恶性病变。将细胞学诊断与后续的组织病理学报告进行比较。
阳性和阴性预测值、诊断准确性、卡方检验等。
研究的病例总数为45例，包括上皮性肿瘤和间叶性肿瘤。年龄范围为15至70岁。在我们的研究中，通过FNA细胞学诊断良性和恶性肿瘤的总体敏感性为86%，特异性为96%，阳性和阴性预测值分别为86%和96%。诊断准确性为93.55%，具有高度统计学意义（P < 0.001）。
FNA细胞学是诊断各种腹膜后肿瘤的一种简单、快速、可靠且成本较低的方法。
