Department of Nuclear Medicine, Shohada e Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ann Nucl Med. 2013 Jun;27(5):478-80. doi: 10.1007/s12149-013-0708-6. Epub 2013 Mar 2.
Osteosarcoma is the most frequent primary malignancy of bone, and usually metastasizes to the lung and bones, while other sites are rare. In most reported cases, soft tissue metastasis of osteosarcoma is unusual, and only develops in the advanced stages of the disease, especially following multiple recurrences. We present a patient with recently diagnosed osteosarcoma of the right femur, showing abdominal wall metastasis diagnosed by technetium-99m-methylene diphosphonate (99m Tc-MDP) whole body bone scintigraphy and confirmed histologically. The present case highlights the importance of whole body imaging of patients with osteosarcoma for detecting unusual sites of metastasis, especially in soft tissue organs.
骨肉瘤是最常见的原发性骨恶性肿瘤,通常转移至肺部和骨骼,而其他部位较为罕见。在大多数报道的病例中,骨肉瘤的软组织转移并不常见,仅在疾病的晚期,特别是多次复发后才会发生。我们报告了一例右侧股骨骨肉瘤患者,该患者经锝-99m 亚甲基二膦酸盐(99mTc-MDP)全身骨扫描诊断为腹壁转移,并经组织学证实。本例强调了对骨肉瘤患者进行全身成像的重要性,以检测异常转移部位,特别是软组织器官。