Heinle A, Carrasquillo J A, Neumann R D
University of Southern California School of Medicine, Los Angeles.
Clin Nucl Med. 1989 Dec;14(12):889-93. doi: 10.1097/00003072-198912000-00006.
Tc-99m MDP bone scintigraphy is widely used for initial staging and subsequent follow-up of patients with osteosarcoma. Two unusual cases are presented here, one with diffuse pleural metastases and one with diffuse peritoneal metastases. In one case, an abnormal bone scan was the first indication of metastatic disease. Both the metastatic pattern of osteosarcoma and the indications for bone scintigraphy are reviewed.
锝-99m亚甲基二膦酸盐骨闪烁显像广泛应用于骨肉瘤患者的初始分期及后续随访。本文介绍两例不寻常的病例，一例有弥漫性胸膜转移，另一例有弥漫性腹膜转移。其中一例，骨扫描异常是转移性疾病的首个迹象。本文对骨肉瘤的转移模式及骨闪烁显像的适应证进行了综述。
