Horváth K, Laub W M
Központi Laboratórium, Heves Megyei Tanács Kórház-Rendelöintézet, Eger.
Orv Hetil. 1990 May 13;131(19):1007-10.
The authors give several data of 357 patients with megaloblastic anaemia diagnosed, treated and controlled between 1958-1988. 334 of the patients had anaemia perniciosa and 23 of them had postresectional megaloblastic anaemia. After listing the criteria of the diagnosis the authors detail the mean age of the patients at the time of diagnosis, the distribution of sexes, age and blood groups among the patients, the number of new cases per year, the frequency of relapsus of the disease and its association with other autoimmune diseases. They also deal with the characteristic seasonal fluctuation and the accumulated cases in families. Its association with malignant tumours, especially with stomach carcinoma was examined.
作者给出了1958年至1988年间诊断、治疗和控制的357例巨幼细胞贫血患者的若干数据。其中334例为恶性贫血患者,23例为切除术后巨幼细胞贫血患者。在列出诊断标准后,作者详细说明了患者诊断时的平均年龄、患者的性别、年龄和血型分布、每年的新病例数、疾病复发频率及其与其他自身免疫性疾病的关联。他们还探讨了其特征性的季节性波动以及家族中的累积病例。研究了其与恶性肿瘤,尤其是与胃癌的关联。