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蛔虫感染强度的测定以及甲苯咪唑治疗后驱虫的动态变化

Measurement of Ascaris lumbricoides infection intensity and the dynamics of expulsion following treatment with mebendazole.

作者信息

Forrester J E, Scott M E

机构信息

Institute of Parasitology, Macdonald College of McGill University, Quebec, Canada.

出版信息

Parasitology. 1990 Apr;100 Pt 2:303-8. doi: 10.1017/s003118200006131x.

DOI:10.1017/s003118200006131x
PMID:2345663
Abstract

Intensity of Ascaris lumbricoides infection was measured in terms of egg counts and worm burden in children 2-10 years of age. The expulsion of A. lumbricoides with a 3-day treatment of mebendazole occurred over 8 days, beginning on the second day of treatment. Ninety-seven percent of the worms were expelled between the second and seventh days. A rapid means of estimating eggs per gram (epg) by the Kato Katz technique correlated well with the method described by Martin & Beaver (1968). In spite of apparent density dependence in egg production, A. lumbricoides egg counts correlated well with worm burdens. It is concluded that, within the context of community surveys, epg is a reasonable means of identifying heavily infected individuals and that epg can be estimated rapidly by a slight modification to the standard Kato Katz technique.

摘要

根据2至10岁儿童的虫卵计数和虫负荷来衡量蛔虫感染强度。用甲苯咪唑进行为期3天的治疗后,蛔虫排出过程持续8天,从治疗的第二天开始。97%的蛔虫在第二天至第七天之间排出。通过改良加藤厚涂片法快速估算每克粪便虫卵数(epg),该方法与Martin和Beaver(1968年)描述的方法相关性良好。尽管蛔虫产卵量存在明显的密度依赖性,但蛔虫虫卵计数与虫负荷相关性良好。得出的结论是,在社区调查中,epg是识别重度感染个体的合理方法,并且通过对标准改良加藤厚涂片法稍作修改就可以快速估算epg。

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