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以体外膜肺氧合作为过渡到移植的桥梁,为患者进行尸体供体肺叶移植。

Cadaveric donor lobar lung transplantation for patients on extracorporeal membrane oxygenation as bridge-to-transplant.

作者信息

Toyoda Yoshiya

机构信息

Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA 19140, USA.

出版信息

Gen Thorac Cardiovasc Surg. 2013 Apr;61(4):197-200. doi: 10.1007/s11748-013-0220-x. Epub 2013 Mar 2.

DOI:10.1007/s11748-013-0220-x
PMID:23456986
Abstract

The total number of lung transplants reported to the International Society of Heart and Lung Transplantation registry continues to increase steadily. In the US, the lung transplant volume has increased from 1172 in 2004 to 1822 in 2011 since lung allocation score system was implemented in 2005 while the overall 1-year survival after transplantation has not changed significantly. One of the most common reasons why lung offers are declined is size-mismatch. Size-reduced lung transplantation including non-anatomical lung volume reduction and lobar lung transplantation is an advanced surgical technique to alleviate donor organ shortage. Living-related donor lung transplantation almost disappeared in the US, but alternatively, we perform lobar transplantation using cadaveric donor lungs. With recent advances in extracorporeal membrane oxygenation (ECMO) technology and surgical experience, ECMO has been used before, during and after lung transplant surgery successfully.

摘要

向国际心肺移植协会登记处报告的肺移植总数持续稳步增长。在美国,自2005年实施肺分配评分系统以来,肺移植数量已从2004年的1172例增加到2011年的1822例,而移植后的总体1年生存率并未显著变化。肺供体被拒绝的最常见原因之一是大小不匹配。减体积肺移植,包括非解剖性肺减容和肺叶移植,是一种缓解供体器官短缺的先进外科技术。在美国,亲属活体供肺移植几乎消失,但取而代之的是,我们使用尸体供肺进行肺叶移植。随着体外膜肺氧合(ECMO)技术的最新进展和手术经验的积累,ECMO已成功应用于肺移植手术的术前、术中和术后。

相似文献

1
Cadaveric donor lobar lung transplantation for patients on extracorporeal membrane oxygenation as bridge-to-transplant.以体外膜肺氧合作为过渡到移植的桥梁,为患者进行尸体供体肺叶移植。
Gen Thorac Cardiovasc Surg. 2013 Apr;61(4):197-200. doi: 10.1007/s11748-013-0220-x. Epub 2013 Mar 2.
2
Efficacy of extracorporeal membrane oxygenation as a bridge to lung transplantation.体外膜肺氧合作为肺移植桥接的疗效。
J Thorac Cardiovasc Surg. 2013 Apr;145(4):1065-1071. doi: 10.1016/j.jtcvs.2012.12.067. Epub 2013 Jan 16.
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An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK.英国肺移植中供体体外肺灌注的观察性研究:DEVELOP-UK。
Health Technol Assess. 2016 Nov;20(85):1-276. doi: 10.3310/hta20850.
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Early airway dehiscence: Risk factors and outcomes with the rising incidence of extracorporeal membrane oxygenation as a bridge to lung transplantation.早期气道裂开:随着体外膜肺氧合作为肺移植桥梁的应用日益增多,其危险因素及结局
J Card Surg. 2019 Oct;34(10):933-940. doi: 10.1111/jocs.14157. Epub 2019 Jul 23.
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Long-term outcomes of bilateral lobar lung transplantation.双侧肺叶移植的长期结果。
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Improving Outcomes in Bridge-to-Transplant: Extended Extracorporeal Membrane Oxygenation Support to Obtain Optimal Donor Lungs for Marginal Recipients.改善桥接移植的结果:延长体外膜肺氧合支持以获得边缘受体的最佳供肺。
ASAIO J. 2019 Jul;65(5):516-521. doi: 10.1097/MAT.0000000000000843.
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Extracorporeal membrane oxygenation as a bridge to lung transplant: midterm outcomes.体外膜肺氧合作为肺移植的桥梁:中期结果。
Ann Thorac Surg. 2011 Oct;92(4):1226-31; discussion 1231-2. doi: 10.1016/j.athoracsur.2011.04.122. Epub 2011 Aug 26.
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J Heart Lung Transplant. 2018 Dec;37(12):1418-1424. doi: 10.1016/j.healun.2018.07.003. Epub 2018 Sep 5.

本文引用的文献

1
Efficacy of extracorporeal membrane oxygenation as a bridge to lung transplantation.体外膜肺氧合作为肺移植桥接的疗效。
J Thorac Cardiovasc Surg. 2013 Apr;145(4):1065-1071. doi: 10.1016/j.jtcvs.2012.12.067. Epub 2013 Jan 16.
2
Contemporary extracorporeal membrane oxygenation for adult respiratory failure: life support in the new era.当代成人呼吸衰竭体外膜肺氧合治疗:新时代的生命支持。
Intensive Care Med. 2012 Feb;38(2):210-20. doi: 10.1007/s00134-011-2439-2. Epub 2011 Dec 7.
3
Update on living-donor lobar lung transplantation.
关于活体供体肺叶移植的最新进展。
Curr Opin Organ Transplant. 2011 Oct;16(5):453-7. doi: 10.1097/MOT.0b013e32834a9997.
4
Should lung transplantation be performed for patients on mechanical respiratory support? The US experience.对于接受机械通气支持的患者,是否应进行肺移植?美国的经验。
J Thorac Cardiovasc Surg. 2010 Mar;139(3):765-773.e1. doi: 10.1016/j.jtcvs.2009.09.031.
5
Matching donor to recipient in lung transplantation: How much does size matter?肺移植中供体与受体的匹配:大小有多重要?
J Thorac Cardiovasc Surg. 2009 May;137(5):1234-40.e1. doi: 10.1016/j.jtcvs.2008.10.024.
6
Impact of graft volume reduction for oversized grafts after lung transplantation on outcome in recipients with end-stage restrictive pulmonary diseases.肺移植后针对过大移植物进行移植物体积缩小对终末期限制性肺疾病受者预后的影响。
J Heart Lung Transplant. 2009 Feb;28(2):130-4. doi: 10.1016/j.healun.2008.11.003.
7
Size-reduced lung transplantation: an advanced operative strategy to alleviate donor organ shortage.减体积肺移植:缓解供体器官短缺的一种先进手术策略。
Transplant Proc. 2004 Nov;36(9):2801-5. doi: 10.1016/j.transproceed.2004.09.066.
8
A decade of living lobar lung transplantation: recipient outcomes.十年肺叶活体肺移植:受者结局
J Thorac Cardiovasc Surg. 2004 Jan;127(1):114-22. doi: 10.1016/j.jtcvs.2003.07.042.
9
Assessment of lungs rejected for transplantation and implications for donor selection.对被拒绝用于移植的肺进行评估及其对供体选择的意义。
Lancet. 2002 Aug 24;360(9333):619-20. doi: 10.1016/s0140-6736(02)09774-x.
10
Pulmonary function in idiopathic pulmonary fibrosis and referral for lung transplantation.特发性肺纤维化的肺功能与肺移植转诊
Am J Respir Crit Care Med. 2001 Jul 1;164(1):103-8. doi: 10.1164/ajrccm.164.1.2007077.