Toyoda Yoshiya
Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Gen Thorac Cardiovasc Surg. 2013 Apr;61(4):197-200. doi: 10.1007/s11748-013-0220-x. Epub 2013 Mar 2.
The total number of lung transplants reported to the International Society of Heart and Lung Transplantation registry continues to increase steadily. In the US, the lung transplant volume has increased from 1172 in 2004 to 1822 in 2011 since lung allocation score system was implemented in 2005 while the overall 1-year survival after transplantation has not changed significantly. One of the most common reasons why lung offers are declined is size-mismatch. Size-reduced lung transplantation including non-anatomical lung volume reduction and lobar lung transplantation is an advanced surgical technique to alleviate donor organ shortage. Living-related donor lung transplantation almost disappeared in the US, but alternatively, we perform lobar transplantation using cadaveric donor lungs. With recent advances in extracorporeal membrane oxygenation (ECMO) technology and surgical experience, ECMO has been used before, during and after lung transplant surgery successfully.
向国际心肺移植协会登记处报告的肺移植总数持续稳步增长。在美国,自2005年实施肺分配评分系统以来,肺移植数量已从2004年的1172例增加到2011年的1822例,而移植后的总体1年生存率并未显著变化。肺供体被拒绝的最常见原因之一是大小不匹配。减体积肺移植,包括非解剖性肺减容和肺叶移植,是一种缓解供体器官短缺的先进外科技术。在美国,亲属活体供肺移植几乎消失,但取而代之的是,我们使用尸体供肺进行肺叶移植。随着体外膜肺氧合(ECMO)技术的最新进展和手术经验的积累,ECMO已成功应用于肺移植手术的术前、术中和术后。