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[使用 I-131 间碘苄胍治疗恶性嗜铬细胞瘤——1 例报告]

[Therapy of malignant pheochromocytoma using I-131 metaiodobenzylguanidine--report of a case].

作者信息

Okazawa H, Endo K, Saga T, Watanabe Y, Nakai T, Kasagi K, Konishi J, Abe M, Goto K, Nakao K

机构信息

Department of Radiology and Nuclear Medicine, Kyoto University Hospital.

出版信息

Nihon Igaku Hoshasen Gakkai Zasshi. 1990 Mar 25;50(3):286-94.

PMID:2345700
Abstract

A 67 year-old-female had multiple metastases to her lung, liver and paraaortic lymph nodes from a post-operative malignant pheochromocytoma. She was treated with 3.7 GBq (100 mCi) of I-131 metaiodobenzylguanidine (MIBG). Metastatic nodules in lung and liver almost disappeared and the secretion of catecholamines decreased than baseline rates. However, major but temporary untoward response, such as hypertension and hyperglycemia, was seen after the I-131 MIBG administration.

摘要

一名67岁女性因术后恶性嗜铬细胞瘤出现肺、肝和腹主动脉旁淋巴结多处转移。她接受了3.7GBq(100mCi)的碘-131间碘苄胍(MIBG)治疗。肺和肝内的转移结节几乎消失,儿茶酚胺分泌较基线水平下降。然而,在给予碘-131 MIBG后出现了严重但短暂的不良反应,如高血压和高血糖。

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