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先天性甲状腺功能减退症伴产后心动过缓。

Congenital hypothyroidism presenting with postpartum bradycardia.

作者信息

Kara Semra, Tayman Cüneyt, Tonbul Alparslan, Andiran Nesibe, Tatli Mansur, Türkay Sadi

机构信息

Division of Neonatology, Fatih University, Medical Faculty, Yenimahalle Ankara, Turkey.

出版信息

J Coll Physicians Surg Pak. 2013 Mar;23(3):214-5.

Abstract

Congenital hypothyroidism is a clinical condition characterized by lack of thyroid hormone because of thyroid gland developmental and thyroid hormone biosynthesis disorders. The most common cause of permanent hypothyroidism is congenital factors. Prompt diagnosis is critical. However, overt signs of hypothyroidism are rarely present at birth, and 95% of affected babies are asymptomatic. Hypoxemia, apnea, acidosis, increased intracranial pressure, vagal stimulus and central nerve system abnormalities represent the most common causes of bradycardia in the neonate. Bradycardia associated with congenital hypothyroidism is very rare. In this paper, a case of severe congenital hypothyroidism, induced by maternal blocker antibodies, who presented with bradycardia, is reported.

摘要

先天性甲状腺功能减退症是一种临床病症,其特征是由于甲状腺发育和甲状腺激素生物合成障碍导致甲状腺激素缺乏。永久性甲状腺功能减退症最常见的原因是先天性因素。及时诊断至关重要。然而,甲状腺功能减退症的明显体征在出生时很少出现,95% 的患病婴儿无症状。低氧血症、呼吸暂停、酸中毒、颅内压升高、迷走神经刺激和中枢神经系统异常是新生儿心动过缓最常见的原因。与先天性甲状腺功能减退症相关的心动过缓非常罕见。本文报道了一例由母体阻断抗体引起的严重先天性甲状腺功能减退症病例,该病例出现了心动过缓。

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