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瑞士耐甲氧西林金黄色葡萄球菌的分子流行病学:仅采集侵袭性分离株不能代表当地克隆多样性的情况。

Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Switzerland: sampling only invasive isolates does not allow a representative description of the local diversity of clones.

机构信息

Service of Hospital Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland.

出版信息

Clin Microbiol Infect. 2013 Jul;19(7):E288-90. doi: 10.1111/1469-0691.12185. Epub 2013 Mar 4.

DOI:10.1111/1469-0691.12185
PMID:23458418
Abstract

We conducted a molecular study of MRSA isolated in Swiss hospitals, including the first five consecutive isolates recovered from blood cultures and the first ten isolates recovered from other sites in newly identified carriers. Among 73 MRSA isolates, 44 different double locus sequence typing (DLST) types and 32 spa types were observed. Most isolates belonged to the NewYork/Japan, the UK-EMRSA-15, the South German and the Berlin clones. In a country with a low to moderate MRSA incidence, inclusion of non-invasive isolates allowed a more accurate description of the diversity.

摘要

我们对瑞士医院分离的耐甲氧西林金黄色葡萄球菌(MRSA)进行了分子研究,包括从血培养中连续分离的前 5 株和新发现的携带者其他部位分离的前 10 株。在 73 株 MRSA 分离株中,观察到 44 种不同的双基因座序列分型(DLST)类型和 32 种 spa 类型。大多数分离株属于纽约/日本、英国-EMRSA-15、南德和柏林克隆。在一个 MRSA 发病率低至中度的国家,包括非侵入性分离株可以更准确地描述其多样性。

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