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儿科人群中的甲状舌管囊肿:与成人甲状舌管囊肿的明显差异。

Thyroglossal cysts in a pediatric population: apparent differences from adult thyroglossal cysts.

作者信息

Pradeep Puthen Veetil, Jayashree Buruju

机构信息

Endocrine Surgery, Narayana Medical College, Andhra Pradesh, India.

出版信息

Ann Saudi Med. 2013 Jan-Feb;33(1):45-8. doi: 10.5144/0256-4947.2013.45.

Abstract

BACKGROUND AND OBJECTIVES

The clinical presentation of thyroglossal cyst and its variation from adult thyroglossal cyst has not been well studied. This study is to determine if the clinical presentation of thyroglossal duct cysts (TGDC) varies between children and adults and whether this affects the optimal management of individual cases.

DESIGN AND SETTING

Retrospective study of all cases operated on for TGDC from February 2008 to November 2011 in a tertiary care teaching hospital.

SUBJECTS AND METHODS

The gender, age, clinical presentation, radiologic imaging, surgical management, post operative complications, and recurrence rates between the children ( 18 years) were compared.

RESULTS

Of the 46 patients, 30 were adults and 16 pediatric; 46.5% of the adults and 74% of the children were females (P=.11). The mean (SD) age in adults was 40.5 (16.0) years, while in children the mean (SD) age was 9.0 (1.4) years, suggesting a bimodal presentation. Hypothyroidism was present in 6.7% of the adults and 56.3% of pediatric cases (P=.0004). Twenty percent of the adults had either an infected TGDC or fistulae, but none of the children had either infection (P=.0001). In both adults and children the duration of disease was significantly shorter in females. In the pediatric group, males had a larger compared to females (P=.006). The most common location of TGDC was the infrahyoid region. The Sistrunk procedure resulted in cure with no recurrences and complications in all.

CONCLUSION

TGDC is commoner in adults with no sex predilection. Children have a shorter duration of disease. Male children present with larger cysts. Hypothyroidism is more common in pediatric TGDC. Infected TGDC and fistulae are uncommon in children. The Sistrunk procedure is adequate for both groups.

摘要

背景与目的

甲状舌管囊肿的临床表现及其与成人甲状舌管囊肿的差异尚未得到充分研究。本研究旨在确定甲状舌管囊肿(TGDC)在儿童和成人中的临床表现是否不同,以及这是否会影响个体病例的最佳治疗。

设计与地点

对2008年2月至2011年11月在一家三级护理教学医院接受TGDC手术的所有病例进行回顾性研究。

对象与方法

比较儿童(18岁)与成人的性别、年龄、临床表现、影像学检查、手术治疗、术后并发症及复发率。

结果

46例患者中,30例为成人,16例为儿童;成人中46.5%为女性,儿童中74%为女性(P = 0.11)。成人的平均(标准差)年龄为40.5(16.0)岁,儿童的平均(标准差)年龄为9.0(1.4)岁,提示呈双峰表现。6.7%的成人和56.3%的儿童存在甲状腺功能减退(P = 0.0004)。20%的成人患有感染性TGDC或瘘管,但儿童均无感染(P = 0.0001)。在成人和儿童中,女性的疾病持续时间均显著较短。在儿童组中,男性囊肿比女性大(P = 0.006)。TGDC最常见的部位是舌骨下区域。Sistrunk手术治愈了所有患者,无复发及并发症。

结论

TGDC在成人中更常见,无性别倾向。儿童的疾病持续时间较短。男童的囊肿更大。甲状腺功能减退在儿童TGDC中更常见。感染性TGDC和瘘管在儿童中不常见。Sistrunk手术对两组均适用。

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本文引用的文献

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Int J Pediatr Otorhinolaryngol. 2003 Dec;67(12):1285-90. doi: 10.1016/j.ijporl.2003.07.006.
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