Guderian R H, Beck B J, Proaño R
Health Care Division, Hospital Vozandes, Quito, Ecuador.
Trans R Soc Trop Med Hyg. 1990 Jan-Feb;84(1):109-12. doi: 10.1016/0035-9203(90)90396-v.
The prevalence of onchocerciasis infection in children aged 1-12 in the Santiago Basin focus, province of Esmeraldas, Ecuador, was determined to see if active transmission of the disease had occurred in the past 6 years. An infection rate of 45.0% was found. Compared to that found in 1980 (14.5%), the infection rate had increased by 210.1%. The increase was greater on the Rio Santiago (340.5%) than on the Rio Cayapas (195.5%). An increase of 286% was seen in the skin microfilarial density in the 1-4 year age group, with a 56.8% increase in the 5-12 year age group. The prevalence of infection in children aged 0-4 years (those born since the first enquiry in 1980) was 64.3%, with an average skin microfilarial density of 12.2 microfilariae (mf)/mg and with 20% presenting nodules, of which 92.1% occurred in the head region. Of the 34 children examined aged less than one year, 25 (73.5%) were positive for microfilariae with an average microfilarial skin density of 9.6 mf/mg. These data suggest that there is active transmission of the disease in the Santiago Basin onchocercal foci.
为了确定厄瓜多尔埃斯梅拉达斯省圣地亚哥河流域疫源地1至12岁儿童的盘尾丝虫病感染率，以此查看在过去6年中该疾病是否有活跃传播。结果发现感染率为45.0%。与1980年发现的感染率（14.5%）相比，感染率增长了210.1%。圣地亚哥河（340.5%）的增长幅度大于卡亚帕斯河（195.5%）。1至4岁年龄组的皮肤微丝蚴密度增长了286%，5至12岁年龄组增长了56.8%。0至4岁儿童（自1980年首次调查以来出生的儿童）的感染率为64.3%，平均皮肤微丝蚴密度为12.2条微丝蚴（mf）/毫克，20%的儿童出现结节，其中92.1%出现在头部区域。在接受检查的34名不满一岁的儿童中，25名（73.5%）微丝蚴呈阳性，平均微丝蚴皮肤密度为9.6 mf/毫克。这些数据表明，圣地亚哥河流域盘尾丝虫病疫源地存在该疾病的活跃传播。
