Molea J, Guderian R H, Proaño R, Carrillo R, Swanson W L
Trans R Soc Trop Med Hyg. 1984;78(1):86-90. doi: 10.1016/0035-9203(84)90183-4.
The frequency, intensity and clinical features of onchocerciasis in the two ethnic groups (Blacks and Chachilla--an indigenous tribe) in the endemic foci of the disease in Esmeraldas province (Ecuador) were evaluated. The incidence of infection and intensity of the disease seen in both groups were directly related to the frequency of man-vector contact and not to racial factors. Both groups showed the same rate of positivity in both the hyperendemic and hypoendemic areas. Males of both groups had a consistently higher positivity rate than did females. The Chachilla were found to have a higher mean microfilarial density than Blacks in both types of endemic areas. Certain clinical features of the disease analogous to those seen in the African form were present only in Blacks. No lymphatic involvement or hypertrophic scarring was seen in the Chachilla, suggesting that in the Blacks there may be a generaically related predisposition to lymphatic complications of microfilarial infections.
对厄瓜多尔埃斯梅拉达斯省疾病流行区两个种族群体（黑人与查查拉——一个原住民部落）的盘尾丝虫病的发病率、严重程度及临床特征进行了评估。在这两个群体中观察到的感染发病率和疾病严重程度与人类-病媒接触频率直接相关，而非种族因素。在高度流行区和低度流行区，两个群体的阳性率相同。两个群体的男性阳性率始终高于女性。发现在两种流行区中，查查拉人的平均微丝蚴密度均高于黑人。该疾病某些类似于非洲型的临床特征仅在黑人中出现。查查拉人未出现淋巴受累或肥厚性瘢痕，这表明黑人可能存在与微丝蚴感染淋巴并发症普遍相关的易感性。
