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四肢瘫痪患者手臂和手部功能的手术恢复

Surgical restoration of arm and hand function in people with tetraplegia.

作者信息

Bryden Anne M, Peljovich Allan E, Hoyen Harry A, Nemunaitis Gregory, Kilgore Kevin L, Keith Michael W

机构信息

The Cleveland FES Center, Case Western Reserve University , Cleveland , Ohio.

出版信息

Top Spinal Cord Inj Rehabil. 2012 Winter;18(1):43-9. doi: 10.1310/sci1801-43.

Abstract

Improved hand and arm function is the most sought after function for people living with a cervical spinal cord injury (SCI). Surgical techniques have been established to increase upper extremity function for tetraplegics, focusing on restoring elbow extension, wrist movement, and hand opening and closing. Additionally, more innovative treatments that have been developed (implanted neuroprostheses and nerve transfers) provide more options for improving function and quality of life. One of the most important steps in the process of restoring upper extremity function in people with tetraplegia is identifying appropriate candidates - typically those with American Spinal Injury Association (ASIA) motor level C5 or greater. Secondary complications of SCI can pose barriers to restoring function, particularly upper extremity spasticity. A novel approach to managing spasticity through high-frequency alternating currents designed to block unwanted spasticity is being researched at the Cleveland FES Center and may improve the impact of reconstructive surgery for these individuals. The impact of these surgeries is best measured within the framework of the World Health Organization's International Classification of Function, Disability and Health. Outcome measures should be chosen to reflect changes within the domains of body functions and structures, activity, and participation. There is a need to strengthen the evidence in the area of reconstructive procedures for people with tetraplegia. Research continues to advance, providing more options for improved function in this population than ever before. The contribution of well-designed outcome studies to this evidence base will ultimately help to address the complications surrounding access to the procedures.

摘要

改善手部和手臂功能是颈脊髓损伤(SCI)患者最渴望获得的功能。已经建立了手术技术来增强四肢瘫痪患者的上肢功能,重点是恢复肘部伸展、手腕活动以及手部的开合。此外,已开发出的更具创新性的治疗方法(植入式神经假体和神经移植)为改善功能和生活质量提供了更多选择。在恢复四肢瘫痪患者上肢功能的过程中,最重要的步骤之一是确定合适的候选人——通常是美国脊髓损伤协会(ASIA)运动水平为C5或更高的患者。SCI的继发性并发症可能会对功能恢复造成障碍,尤其是上肢痉挛。克利夫兰功能性电刺激中心正在研究一种通过高频交流电来控制痉挛的新方法,旨在阻断不必要的痉挛,这可能会改善这些患者重建手术的效果。这些手术的效果最好在世界卫生组织的《国际功能、残疾和健康分类》框架内进行衡量。应选择能够反映身体功能和结构、活动及参与等领域变化的结果指标。需要加强针对四肢瘫痪患者重建手术领域的证据。研究不断推进,为这一人群提供了比以往更多的改善功能的选择。精心设计的结果研究对这一证据基础的贡献最终将有助于解决围绕手术可及性的并发症问题。

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