Bukharova I K, Osokina L I, Revazova E S, Moroz L V
Vopr Onkol. 1990;36(4):448-51.
Plant polysaccharide palyustran inhibited the growth of human lung carcinoma P-1 transplanted to athymic mice by 60% but failed to do so in human rhabdomyosarcoma. Treatment with palyustran was followed by a 2-fold decrease in lympho- and granulocyte levels, selective inhibition of succinate dehydrogenase and alpha-glycerophosphate dehydrogenase activity in tumor cells and--in single cases--metastatic involvement of the liver.
植物多糖帕柳聚糖可抑制移植到无胸腺小鼠体内的人肺癌P-1的生长，抑制率达60%，但对人横纹肌肉瘤无效。用帕柳聚糖治疗后，淋巴细胞和粒细胞水平下降两倍，肿瘤细胞中的琥珀酸脱氢酶和α-磷酸甘油脱氢酶活性受到选择性抑制，个别病例出现肝脏转移。
