Sharafetdinov Kh Kh, Denisov L N, Samsonov G R, Pokrovskaia G R, Voĭtko N E
Vopr Pitan. 1990 Jan-Feb(1):18-22.
The main requirements for the dietotherapy of rheumatoid arthritis (RA) patients have been formulated, and for the first time a pathogenetically balanced diet has been developed that produces antiinflammatory and immunocorrective effects. The effectiveness of the dietotherapy included into the combined treatment was studied in 41 patients with classic and proved RA. The authors have studied the influence of the dietotherapy on the clinical signs characterizing the activity of inflammation in the joints, and laboratory immunological parameters (IgG, IgM, IgA, IgD, the complement components: C1-inhibitor, C3, C4, C5, C9; haptoglobin, orrhozomucoid, transferrin, ceruloplasmin, alpha 1-antitrypsin, alpha 2-macroglobulin, prealbumin). The results of the study have shown that the dietotherapy is not only conducive to the improvement of the clinical picture of the disease, that permits diminishing the amount of nonsteroid antiinflammatory drugs used, but also produces a favourable effect on the RA patients' immunological state. It has been concluded that inclusion of the dietotherapy into the combined treatment of RA patients is advisable.
已制定出类风湿性关节炎(RA)患者饮食疗法的主要要求,并且首次研发出一种具有致病平衡性的饮食方案,该方案具有抗炎和免疫纠正作用。在41例典型且确诊的RA患者中研究了纳入联合治疗的饮食疗法的有效性。作者研究了饮食疗法对表征关节炎症活动的临床体征以及实验室免疫学参数(IgG、IgM、IgA、IgD、补体成分:C1抑制剂、C3、C4、C5、C9;触珠蛋白、类粘蛋白、转铁蛋白、铜蓝蛋白、α1抗胰蛋白酶、α2巨球蛋白、前白蛋白)的影响。研究结果表明,饮食疗法不仅有助于改善疾病的临床表现,减少非甾体抗炎药的使用量,而且对RA患者的免疫状态产生有益影响。得出的结论是,将饮食疗法纳入RA患者的联合治疗是可取的。