Gapparov M M, Virovets O A
Vopr Pitan. 1990 Jan-Feb(1):36-40.
The nonenzymatic glycosylation of human plasma albumin by glucose, fructose, xylose, glucose-6-P, fructose-6-P, 6-PP was studied in vitro. The most manifest differences in the albumin spectrum (250-390 nm) were observed when fructose-6-P and xylose were used. The use of 3H-glucose and 14C-fructose has shown that there are 2 sites for glucose addition, 4 sites for fructose addition and 1 site to which both glucose and fructose can be bound, but glucose is preferable. Calf thymus DNA has 10 sites to which carbohydrate can be bound: 4 for glucose and 6 for fructose, only.
在体外研究了葡萄糖、果糖、木糖、6-磷酸葡萄糖、6-磷酸果糖、6-磷酸磷酸酯对人血浆白蛋白的非酶糖基化作用。当使用6-磷酸果糖和木糖时，在白蛋白光谱（250 - 390纳米）中观察到最明显的差异。使用³H-葡萄糖和¹⁴C-果糖表明，有2个葡萄糖添加位点、4个果糖添加位点以及1个葡萄糖和果糖均可结合但葡萄糖更优先结合的位点。小牛胸腺DNA有10个可与碳水化合物结合的位点：仅4个用于葡萄糖结合，6个用于果糖结合。
