Nascimento Ozanildo V, Boleti Ana P A, Yuyama Lucia K O, Lima Emerson S
Universidade Federal do Amazonas, Faculdade de Educação Física e Fisioterapia, 69077-000, Manaus, AM, Brasil.
An Acad Bras Cienc. 2013 Mar;85(1):355-63. doi: 10.1590/s0001-37652013005000001. Epub 2013 Mar 1.
Amazonian Camu-camu fruit (Myrciaria dubia HBK Mc Vaugh) has attracted interest from food and cosmetics industries because of its rich content of vitamin C, flavonoids and anthocyanins. The goal of this study was investigates the antiobesity action of the ingestion of the Camu-camu pulp in a rat model of diet-induced obesity. Wistar rats with obesity induced by subcutaneous injection of monosodium glutamate receiving diet ad libitum. The rats were divided in two groups: an experimental group that ingested 25 mL/day of Camu-camu pulp (CCG) and a non treated group (CG). After 12 weeks, the animals were sacrificed. Blood, liver, heart, white adipose tissues were collected and weighted, biochemical and inflammatory profiles were determinate as well. Animals that received the pulp of Camu-camu reduced their weights of the fat in white adipose tissues, glucose, total cholesterol, triglycerides, LDL-c and insulin blood levels. There was an increase in HDL-c levels. No change was observed in inflammatory markers and liver enzymes. Camu-camu pulp was able to improve the biochemical profile of obesity in rats suggesting that this Amazonian fruit can be further used such a functional food ingredient in control of chronic diseases linked to obesity.
亚马逊卡姆果（Myrciaria dubia HBK Mc Vaugh）因其富含维生素C、黄酮类化合物和花青素，已引起食品和化妆品行业的关注。本研究的目的是在饮食诱导肥胖的大鼠模型中，研究摄入卡姆果果肉的抗肥胖作用。通过皮下注射谷氨酸钠诱导肥胖的Wistar大鼠自由进食。将大鼠分为两组：实验组每天摄入25毫升卡姆果果肉（CCG），另一组为未处理组（CG）。12周后，处死动物。收集血液、肝脏、心脏、白色脂肪组织并称重，同时测定生化和炎症指标。摄入卡姆果果肉的动物白色脂肪组织中的脂肪重量、血糖、总胆固醇、甘油三酯、低密度脂蛋白胆固醇和胰岛素血液水平均有所降低。高密度脂蛋白胆固醇水平有所升高。炎症标志物和肝酶未观察到变化。卡姆果果肉能够改善大鼠肥胖的生化指标，表明这种亚马逊水果可进一步用作功能性食品成分，以控制与肥胖相关的慢性疾病。
