Neuroscience Education Institute, Carlsbad, CA, USA.
CNS Spectr. 2012 Nov;17 Suppl 1:10-21. doi: 10.1017/S1092852912000739.
Antipsychotics are the mainstay of treatment for patients with schizophrenia. However, these medications only work if they are taken and perhaps work best if they are taken for longer periods of time than seen in typical research trials. Here we explore the idea of "time as drug" by reviewing the data showing the potential benefits of long-term antipsychotic use. We also discuss the utility of depot antipsychotic formulations for improving the chances of attaining long-term therapeutic results.
抗精神病药是精神分裂症患者治疗的主要手段。然而，这些药物只有在服用时才有效，如果服用时间超过典型研究试验中所见的时间，可能效果最佳。在这里，我们通过回顾显示长期使用抗精神病药物潜在益处的数据，探讨了“时间即药物”的理念。我们还讨论了长效抗精神病药物制剂在提高获得长期治疗效果机会方面的效用。
